Placebo: Normal saline

DRUG7 trials

Conditions

Chemical TerrorismChemical WarfareChronic Obstructive Pulmonary DiseaseFractures, OpenHealthy ParticipantsHealthy VolunteersInfectionNon-cystic Fibrosis Bronchiectasis

Phase 1

Pharmacokinetic (PK) and Safety Study of Plasma-derived Human Butyrylcholinesterase Administered Intravenously

CompletedNCT00333515

Baxalta now part of ShireChemical Terrorism, Chemical Warfare, Healthy Volunteers

Start: 2007-01-01End: 2008-08-01Updated: 2021-05-05

A Study of Plasma-Derived Human Butyrylcholinesterase Administered Intramuscularly

CompletedNCT00333528

Baxalta now part of ShireHealthy Volunteers

Start: 2007-12-01End: 2008-08-01Updated: 2021-05-05

Inflammatory Response In Schizophrenia

CompletedNCT03093064

King's College LondonSchizophrenia

Start: 2017-04-01End: 2023-08-07Updated: 2024-03-08

A Phase 1a/1b Study to Investigate the Safety, Tolerability, Microbiological Response, and Pharmacokinetics of Inhaled Rev-56 in Adult Healthy Volunteers and Adult Non-cystic Fibrosis Bronchiectasis (NCFB) Patients With Chronic P. Aeruginosa

Not yet recruitingNCT07709494

Revagenix, Inc.Healthy Participants, Non-cystic Fibrosis Bronchiectasis

Start: 2026-07-01End: 2027-06-01Target: 64Updated: 2026-07-16

Phase 3

Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures

TerminatedNCT03705962

University of VirginiaFractures, Open

Start: 2015-07-31End: 2019-03-07Updated: 2023-06-15

Phase 4

Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD

CompletedNCT00754546

Dartmouth-Hitchcock Medical CenterChronic Obstructive Pulmonary Disease

Start: 2008-08-31End: 2009-05-31Updated: 2013-05-29

Unknown Phase

Antibiotic Irrigation for Pancreatoduodenectomy

CompletedNCT02186457

Indiana UniversityInfection, Surgery

Start: 2014-11-30End: 2019-08-31Updated: 2022-02-23

2025-12-01

412. TARGETING MICROGLIAL ACTIVATION IN SCHIZOPHRENIA: A LONGITUDINAL [18F]DPA-714 PET IMAGING STUDY INVESTIGATING THE EFFECTS OF A 3-MONTH TREATMENT WITH NATALIZUMAB

The International Journal of Neuropsychopharmacology2025-08-01

MICROGLIAL ACTIVATION IN MEDICATED PATIENTS WITH FIRST-EPISODE PSYCHOSIS: PRELIMINARY RESULTS FROM A [18F]DPA-714 PET IMAGING STUDY

The International Journal of Neuropsychopharmacology2025-02-011 citations

Advantages of endurance treadmill walking compared with cycling to assess bronchodilator therapy.

2009-12-2911 citations