placebo+metformin

DRUG2 trials

Sponsors

Hoffmann-La Roche, Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.

Conditions

Diabetes Mellitus Type 2Type2 Diabetes

Phase 2

A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)

CompletedNCT04998032

Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.Type2 Diabetes

Start: 2021-10-12End: 2023-08-13Updated: 2024-12-06

Phase 3

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

CompletedNCT01691846

Hoffmann-La RocheDiabetes Mellitus Type 2

Start: 2012-10-31End: 2013-09-30Updated: 2017-02-23

Related Papers

Efsubaglutide alfa added to metformin improves glycaemia with β-cell functional responses in type 2 diabetes: a randomised, double-blind, placebo-controlled, two-stage adaptive phase 2b/3 trial (SUPER 2)

Nature Communications2026-05-08

Exposure-Response Analysis of Efsubaglutide Alfa in Patients with Type 2 Diabetes Treated with Metformin.

2025-09-24

Population Pharmacokinetics of Efsubaglutide Alfa in Healthy Subjects and Subjects with Type 2 Diabetes.

2025-02-177 citations

778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes

Diabetes2023-06-205 citations