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Placebo Subcutaneous injection

DRUG5 trials

Sponsors

Hospital for Special Surgery, New York, The University of Texas Health Science Center at San Antonio, Novartis Pharmaceuticals, Biocad, University of Aarhus

Conditions

Axial SpondyloarthritisChronic Migraine, HeadacheGlucose Tolerance ImpairedHeadache DisordersInsulin SensitivityMigraineMigraine With or Without AuraSystemic Sclerosis

Early Phase 1

Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
CompletedNCT05093517
The University of Texas Health Science Center at San AntonioGlucose Tolerance Impaired, Insulin Sensitivity, Type 2 Diabetes
Start: 2021-11-10End: 2022-03-16Updated: 2024-08-09

Phase 2

Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis
RecruitingNCT03844061
Hospital for Special Surgery, New YorkSystemic Sclerosis
Start: 2019-07-29End: 2026-06-30Target: 30Updated: 2026-03-27
Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD)
CompletedNCT05454410
Novartis PharmaceuticalsTreatment-Resistant Depression
Start: 2023-03-13End: 2023-11-28Updated: 2025-04-13

Phase 3

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)
Active, not recruitingNCT06333210
BiocadAxial Spondyloarthritis
Start: 2023-12-25End: 2028-02-29Target: 421Updated: 2024-06-03

Unknown Phase

New Methods for Evaluating Preventive Migraine Treatment
RecruitingNCT07071506
University of AarhusChronic Migraine, Headache, Headache Disorders, Migraine +1
Start: 2025-06-19End: 2028-09-01Target: 60Updated: 2026-05-19