Placebo semaglutide
Sponsors
Novo Nordisk A/S
Conditions
Diabetes Mellitus, Type 2ObesityObesity or OverweightOverweightParticipants with overweight or obesityType 2 Diabetes Mellitusand type 2 diabetes
Phase 1
Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 Diabetes
CompletedNCT06403761
Start: 2024-05-06End: 2026-02-02Updated: 2026-02-27
The Role of the Amylin Analogue Cagrilintide in Bone Metabolism
RecruitingNCT07010432
Start: 2025-06-12End: 2028-05-03Target: 144Updated: 2025-07-25
Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)
RecruitingNCT07527195
Start: 2026-04-10End: 2028-06-09Target: 100Updated: 2026-05-07
Phase 3
A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
CompletedNCT05394519
Start: 2023-02-01End: 2025-02-03Updated: 2026-01-28
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range
CompletedNCT05564117
Start: 2022-10-11End: 2024-05-07Updated: 2026-02-25
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
Active, not recruitingNCT05567796
Start: 2022-11-01End: 2026-10-19Target: 3400Updated: 2026-05-05
A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight
CompletedNCT05813925
Start: 2023-04-03End: 2025-03-07Updated: 2026-01-22
A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight
CompletedNCT05996848
Start: 2023-08-15End: 2025-02-22Updated: 2026-01-09
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
CompletedNCT06065540
Start: 2023-09-27End: 2026-01-06Updated: 2026-01-22
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
Active, not recruitingNCT06780449
Start: 2025-02-10End: 2028-10-31Target: 400Updated: 2026-01-20
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
RecruitingNCT07253285
Start: 2026-01-08End: 2033-09-20Target: 460Updated: 2026-04-02
Efficacy and safety of NNC0487-0111 s.c. once-weekly compared to semaglutide s.c. once-weekly in participants with overweight or obesity, and type 2 diabetes (AMAZE 8)
Not yet recruitingCTIS2024-520446-31-00
Target: 85Updated: 2026-05-15