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Placebo semaglutide

DRUG12 trials

Sponsors

Novo Nordisk A/S

Conditions

Diabetes Mellitus, Type 2ObesityObesity or OverweightOverweightParticipants with overweight or obesityType 2 Diabetes Mellitusand type 2 diabetes

Phase 1

Phase 3

A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
CompletedNCT05394519
Novo Nordisk A/SObesity, Overweight, Type 2 Diabetes Mellitus
Start: 2023-02-01End: 2025-02-03Updated: 2026-01-28
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range
CompletedNCT05564117
Novo Nordisk A/SObesity, Overweight
Start: 2022-10-11End: 2024-05-07Updated: 2026-02-25
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
Active, not recruitingNCT05567796
Novo Nordisk A/SObesity
Start: 2022-11-01End: 2026-10-19Target: 3400Updated: 2026-05-05
A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight
CompletedNCT05813925
Novo Nordisk A/SObesity or Overweight
Start: 2023-04-03End: 2025-03-07Updated: 2026-01-22
A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight
CompletedNCT05996848
Novo Nordisk A/SObesity or Overweight
Start: 2023-08-15End: 2025-02-22Updated: 2026-01-09
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
CompletedNCT06065540
Novo Nordisk A/SType 2 Diabetes Mellitus
Start: 2023-09-27End: 2026-01-06Updated: 2026-01-22
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
Active, not recruitingNCT06780449
Novo Nordisk A/SObesity
Start: 2025-02-10End: 2028-10-31Target: 400Updated: 2026-01-20
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
RecruitingNCT07253285
Novo Nordisk A/SObesity, Overweight
Start: 2026-01-08End: 2033-09-20Target: 460Updated: 2026-04-02
Efficacy and safety of NNC0487-0111 s.c. once-weekly compared to semaglutide s.c. once-weekly in participants with overweight or obesity, and type 2 diabetes (AMAZE 8)
Not yet recruitingCTIS2024-520446-31-00
Novo Nordisk A/Sand type 2 diabetes, Participants with overweight or obesity
Target: 85Updated: 2026-05-15

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