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Placebo procedure

PROCEDURE4 trials

Sponsors

United States Naval Medical Center, San Diego, Imperial College London, King's College London

Conditions

Coronary Artery DiseaseHeart Failure With Preserved Ejection Fraction (HFPEF)Hypertrophic CardiomyopathyPost Traumatic Stress Disorder (PTSD)Refractory Angina

Phase 2

A Randomized, Placebo-Controlled Trial of Stellate Ganglion Block in the Treatment of Post Traumatic Stress Disorder
CompletedNCT01629537
United States Naval Medical Center, San DiegoPost Traumatic Stress Disorder (PTSD)
Start: 2011-06-30End: 2016-04-30Target: 41Updated: 2017-03-30
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
RecruitingNCT07560436
King's College LondonCoronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
Start: 2026-03-23End: 2029-08-01Target: 350Updated: 2026-05-01

Unknown Phase

Coronary Sinus Reducer Objective Impact on Symptoms, MRI Ischaemia and Microvascular Resistance
NCT04892537
Imperial College LondonRefractory Angina
Start: 2021-05-21End: 2024-01-31Target: 50Updated: 2023-10-30
Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathy
Not yet recruitingNCT07865364
Imperial College LondonHypertrophic Cardiomyopathy
Start: 2026-10-01End: 2029-09-01Target: 50Updated: 2026-10-08

Related Papers

Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial.
2024-04-0849 citations
A double-blind, randomised, placebo-controlled trial of the coronary sinus Reducer in refractory angina: design and rationale of the ORBITA-COSMIC trial
EuroIntervention2024-02-014 citations
A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina
New England Journal of Medicine2023-11-11174 citations