Placebo multiple ascending dose

DRUG2 trials

Sponsors

Pfizer, 7 Hills Pharma, LLC

Conditions

Healthy SubjectsSolid Tumor

Phase 1

Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.

CompletedNCT02793232

PfizerHealthy Subjects

Start: 2016-06-13End: 2017-01-05Updated: 2018-09-17

A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects

CompletedNCT04508179

7 Hills Pharma, LLCSolid Tumor

Start: 2020-10-28End: 2021-10-25Updated: 2021-11-02

Related Papers

603 A randomized, placebo-controlled, first in human phase I single ascending dose (SAD) and multiple ascending dose (MAD) study in healthy male volunteers of the immunostimulant 7HP349

Regular and Young Investigator Award Abstracts2022-11-011 citations

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects

Journal of Alzheimer s Disease2019-08-1624 citations