Placebo inhalation solution

DRUG6 trials

Sponsors

United Therapeutics, GlaxoSmithKline, Boehringer Ingelheim, Gerard Turino, Spyryx Biosciences, Inc.

Conditions

Alpha 1-Antitrypsin DeficiencyAsthmaCOPDCOPD (Chronic Obstructive Pulmonary Disease)Cystic FibrosisEmphysemaHealthyHealthy Smoker

Phase 1

Inhaled RB042 in Healthy Adult Volunteers, Healthy Adult Smokers and Patients With Chronic Obstructive Pulmonary Disease

RecruitingNCT07285122

Atisama TherapeuticsCOPD, COPD (Chronic Obstructive Pulmonary Disease), Healthy +1

Start: 2026-02-16End: 2027-10-01Target: 105Updated: 2026-08-12

Phase 2

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

CompletedNCT03114020

Gerard TurinoAlpha 1-Antitrypsin Deficiency, Emphysema

Start: 2017-03-22End: 2019-11-12Updated: 2020-04-21

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis

CompletedNCT03229252

Spyryx Biosciences, Inc.Cystic Fibrosis

Start: 2017-08-01End: 2019-06-20Updated: 2019-12-30

Phase 3

Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH)

CompletedNCT00147199

United TherapeuticsPulmonary Hypertension

Start: 2005-06-30End: 2007-10-31Updated: 2024-01-02

Nebulized Fluticasone Propionate VS Oral Prednisone in Chinese Pediatric and Adolescent Subjects With an Acute Exacerbation of Asthma

CompletedNCT01687296

GlaxoSmithKlineAsthma

Start: 2012-11-12End: 2013-06-21Updated: 2018-06-20

Ipratropium Bromide/Salbutamol Delivered by the Respimat® Inhaler Compared to Ipratropium Bromide Respimat®, COMBIVENT® Inhalation Aerosol and Placebo in Adults With Chronic Obstructive Pulmonary Disease

CompletedNCT02177253

Boehringer IngelheimPulmonary Disease, Chronic Obstructive

Start: 2002-10-31Updated: 2014-06-27

Related Papers

First clinical trials of the inhaled epithelial sodium channel inhibitor BI 1265162 in healthy volunteers

ERJ Open Research2020-12-109 citations

Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial.

2010-05-01386 citations