Placebo Film

DRUG10 trials

Conditions

AgitationAgitation Associated With Bipolar DisorderAgitation,PsychomotorBipolar DisorderBipolar Disorder IBipolar Disorder IIDeliriumDementia

Phase 1

Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV

CompletedNCT02579083

KBio IncHerpes Simplex Infections, HIV

Start: 2016-01-31End: 2018-07-31Updated: 2023-11-14

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

CompletedNCT04010305

BioXcel Therapeutics IncAgitation, Schizophrenia

Start: 2019-05-22End: 2019-07-31Updated: 2026-08-11

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

RecruitingNCT05025605

BioXcel Therapeutics IncBipolar Disorder I, Bipolar Disorder II, Schizo-Affective Disorder +2

Start: 2021-08-27End: 2027-12-31Target: 140Updated: 2026-08-11

Phase 2

Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain

CompletedNCT00941304

BioDelivery Sciences InternationalDental Pain

Start: 2009-08-31End: 2009-11-30Updated: 2017-02-27

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

CompletedNCT01871285

BioDelivery Sciences InternationalPain

Start: 2013-06-30End: 2014-07-31Updated: 2017-02-27

An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia

TerminatedNCT05276830

BioXcel Therapeutics IncAgitation, Dementia

Start: 2022-02-08End: 2022-04-01Updated: 2026-08-11

Study of BXCL501 In Agitation Associated With Delirium in ICU Patients

WithdrawnNCT05313386

BioXcel Therapeutics IncAgitation, Delirium

Start: 2021-02-23End: 2022-02-21Updated: 2026-08-11

Phase 3

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia

CompletedNCT04268303

BioXcel Therapeutics IncAgitation, Schizoaffective Disorder, Schizo Affective Disorder +2

Start: 2020-01-24End: 2020-05-06Updated: 2026-08-11

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder

CompletedNCT04276883

BioXcel Therapeutics IncAgitation Associated With Bipolar Disorder, Agitation,Psychomotor, Bipolar Disorder

Start: 2020-02-24End: 2020-05-21Updated: 2026-08-11

Unknown Phase

Vaginal Film Administration and Placement Study: FLAG

CompletedNCT02908503

University of PittsburghHealthy Women

Start: 2016-07-31End: 2017-02-14Updated: 2018-07-05

Related Papers

Sublingual Dexmedetomidine for the Treatment of Acute Agitation in Adults With Schizophrenia or Schizoaffective Disorder

The Journal of Clinical Psychiatry2022-09-2924 citations

Sublingual Dexmedetomidine for Agitation Associated with Schizophrenia or Bipolar Disorder: A Post Hoc Analysis of Number Needed to Treat, Number Needed to Harm, and Likelihood to be Helped or Harmed

Advances in Therapy2022-08-249 citations

Effect of Sublingual Dexmedetomidine vs Placebo on Acute Agitation Associated With Bipolar Disorder

JAMA2022-02-2278 citations

Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial

PLoS Medicine2021-02-0354 citations