Placebo Comparator: Placebo

DRUG17 trials

Conditions

Abuse CannabisAcute Ischemic StrokeAlcoholCaffeineCalcific Uremic ArteriolopathyCalciphylaxisChronic Fatigue SyndromeCorneal Ulcer

Phase 1

Trial LEP-F1 + GLA-SE in Healthy Adult in Areas Endemic for Leprosy

Not yet recruitingNCT06627257

The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)Leprosy

Start: 2025-01-02End: 2026-08-31Target: 54Updated: 2024-10-04

High Potency Cannabis: Acute and Protracted Effects

RecruitingNCT06859723

University of California, Los AngelesAbuse Cannabis, Pain, Pharmacokinetics

Start: 2025-07-03End: 2028-07-01Target: 30Updated: 2025-10-06

Phase 2

Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking

CompletedNCT00218465

Massachusetts General HospitalNicotine Dependence

Start: 2006-08-31End: 2009-06-30Updated: 2017-03-24

Clinical Trial to Investigate Efficacy of LAS41004 in Psoriasis

CompletedNCT01283698

Almirall, S.A.Psoriasis

Start: 2011-01-31End: 2011-03-31Target: 20Updated: 2015-05-29

Immunogenicity, Safety, Tolerability of a Plant-made H5 Virus-like-particle (VLP) Influenza Vaccine.

CompletedNCT01991561

MedicagoRespiratory Tract Diseases, Respiratory Tract Infections, RNA Virus Infections +1

Start: 2013-06-30End: 2014-11-30Updated: 2020-06-11

TUC3PII-01_TU2670 Phase IIa Clinical Study

CompletedNCT05138562

TiumBio Co., Ltd.Endometriosis

Start: 2021-08-19End: 2024-08-05Updated: 2024-08-13

Phase 3

Phase 3 Study of SNF472 for Calciphylaxis

CompletedNCT04195906

Sanifit Therapeutics S. A.Calcific Uremic Arteriolopathy, Calciphylaxis

Start: 2020-02-12End: 2022-10-24Updated: 2024-02-20

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

CompletedNCT04770220

Alzheon Inc.Early Alzheimer's Disease

Start: 2021-05-19End: 2024-07-29Updated: 2025-11-07

Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

RecruitingNCT06658002

University of California, San FranciscoCorneal Ulcer, Fungal Keratitis

Start: 2025-09-01End: 2027-09-01Target: 150Updated: 2026-06-05

Phase 4

BEFORE Study, Efficacy of Refigura

CompletedNCT03557424

Heilpflanzenwohl AGEfficacy, Self, Overweight and Obesity, Weight Loss

Start: 2017-04-26End: 2018-04-16Updated: 2018-06-15

Unknown Phase

Folic Acid and Zinc Supplementation Trial (FAZST)

CompletedNCT01857310

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Live Birth, Pregnancy, Spontaneous Abortion

Start: 2013-06-30End: 2019-06-30Updated: 2020-11-19

Crave Crush Behavioral Study

CompletedNCT02744885

Oregon Research Behavioral Intervention Strategies, Inc.Obesity

Start: 2016-02-29End: 2016-04-30Updated: 2018-07-19

Effect of Ginko and Cistanche Against Fatigue Symptoms

CompletedNCT02807649

Access Business GroupChronic Fatigue Syndrome, Fatigue, Mental Fatigue

Start: 2015-05-31End: 2015-12-31Updated: 2016-06-21

Effects of a Multispecies Probiotic on Migraine

NCT04696458

Scripps HealthHeadache, Migraine, Irritable Bowel Syndrome, Migraine

Start: 2021-04-15End: 2024-04-01Target: 60Updated: 2022-11-23

Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stroke With Large Vessel Occlusion

RecruitingNCT06211712

Huashan HospitalAcute Ischemic Stroke

Start: 2024-04-17End: 2025-12-31Target: 120Updated: 2024-12-04

Mobile Shared Decision-Making Program for ICU Caregivers

CompletedNCT07469878

CHIA-HUI MATerminally Ill Patients

Start: 2021-08-28End: 2022-11-09Updated: 2026-03-13

Investigating the Effect of Caffeine and Alcohol on Pupil Dynamics

RecruitingNCT07625358

National University of SingaporeAlcohol, Caffeine, Eye Movements +4

Start: 2026-06-01End: 2027-11-05Target: 100Updated: 2026-06-04

2026-03-24

Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial

Drugs2025-09-281 citations

Clinical Pharmacokinetics of Oral ALZ-801/Valiltramiprosate in a 2-Year Phase 2 Trial of APOE4 Carriers with Early Alzheimer’s Disease

Clinical Pharmacokinetics2025-02-052 citations

Phase 3 Trial of Oral Anti‐Amyloid Agent ALZ‐801/Valiltramiprosate in APOE4/4 Homozygotes with Early Alzheimer’s Disease: Baseline Characteristics and Prevalence of Comorbid Cerebral Amyloid Angiopathy

Alzheimer s & Dementia2024-12-01

Effect of an 18-month meditation training on cardiovascular risk in older adults: a secondary analysis of the Age-Well randomized controlled trial.

2024-11-16

Reliability of the assessment of the clinical dementia rating scale from the analysis of medical records in comparison with the reference method.

2024-09-0510 citations

Target trial emulation of preconception serum vitamin D status on fertility outcomes: a couples-based approach.

2024-08-20

Hexasodium fytate for the treatment of calciphylaxis: a randomised, double-blind, phase 3, placebo-controlled trial with an open-label extension.

2024-08-1610 citations

Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer’s Disease

Drugs2024-06-2023 citations

Patient-Reported and Clinical Outcomes Among Patients With Calciphylaxis.

2023-01-243 citations

A Botanical Product Containing Cistanche and Ginkgo Extracts Potentially Improves Chronic Fatigue Syndrome Symptoms in Adults: A Randomized, Double-Blind, and Placebo-Controlled Study

Frontiers in Nutrition2021-11-2610 citations

The impact of zinc and folic acid supplementation on sperm DNA methylation: results from the folic acid and zinc supplementation randomized clinical trial (FAZST).

2021-10-1423 citations

Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment

JAMA2020-01-07160 citations

Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial.

2018-01-2355 citations

Gymnemic acids lozenge reduces short-term consumption of high-sugar food: A placebo controlled experiment

Journal of Psychopharmacology2017-09-2515 citations