Placebo colchicine

DRUG4 trials

Sponsors

Population Health Research Institute, Beijing Tiantan Hospital, Brazilian Clinical Research Institute

Conditions

Atrial FibrillationIschemic StrokeStrokeTIAThoracic Surgery

Phase 3

Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot Study

CompletedNCT01985425

Population Health Research InstituteAtrial Fibrillation, Thoracic Surgery

Start: 2014-04-30End: 2015-09-30Updated: 2021-11-05

Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)

CompletedNCT05439356

Beijing Tiantan HospitalIschemic Stroke, TIA

Start: 2022-08-11End: 2024-04-12Updated: 2024-06-25

Colchicine for Secondary Prevention After Ischemic Stroke (CHANCE-3 EX)

Not yet recruitingNCT07035405

Beijing Tiantan HospitalStroke

Start: 2025-07-04End: 2028-12-31Target: 7500Updated: 2025-06-27

Phase 4

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke

Not yet recruitingNCT06396858

Brazilian Clinical Research InstituteIschemic Stroke

Start: 2026-07-01End: 2027-12-01Target: 4500Updated: 2026-02-11

Related Papers

Colchicine for preventing stroke in patients with and without intracranial atherosclerotic stenosis: a prespecified analysis of a randomized clinical trial.

2025-05-19

Colchicine in patients with acute ischaemic stroke or transient ischaemic attack (CHANCE-3): multicentre, double blind, randomised, placebo controlled trial

BMJ2024-06-2675 citations

Colchicine in High-risk Patients with Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3): Rationale and design of a multicenter randomized placebo-controlled trial

International Journal of Stroke2023-04-1518 citations