Placebo Aspirin

DRUG3 trials

Sponsors

University of Oxford, Newcastle-upon-Tyne Hospitals NHS Trust, Dr. med. Mahir Karakas

Conditions

Acute Chest SyndromeChronic Obstructive Pulmonary Disease (COPD)Diabetes Mellitus

Phase 2

Anti-platelet Therapy in the Prevention of Cardiovascular Disease in Patients With COPD (APPLE-COPD: ICON 2)

CompletedNCT03487406

Newcastle-upon-Tyne Hospitals NHS TrustChronic Obstructive Pulmonary Disease (COPD)

Start: 2015-09-30End: 2017-11-30Updated: 2018-04-04

Phase 3

Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin

TerminatedNCT03820466

Dr. med. Mahir KarakasAcute Chest Syndrome

Start: 2020-02-21End: 2022-04-07Updated: 2022-05-24

Phase 4

ASCEND: A Study of Cardiovascular Events iN Diabetes

Active, not recruitingNCT00135226

University of OxfordDiabetes Mellitus

Start: 2005-03-31End: 2037-07-31Updated: 2025-05-28

Related Papers

Number needed to treat to avoid progression or death: Zanubrutinib vs other COVALENT bruton tyrosine kinase inhibitors in Relapsed/Refractory chronic lymphocytic leukemia

Blood2025-11-03

Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes

BMJ Open2025-02-012 citations

Effects of aspirin and omega-3 fatty acids on composite and subdomain scores from the NEI-VFQ-25 questionnaire: the ASCEND-Eye randomized controlled trial.

2024-11-05

ASCEND-Eye: Rationale, design and baseline characteristics for a sub-study of the ASCEND randomised trial, exploring the effects of aspirin and omega-3 fatty acids on diabetic retinopathy and age-related macular degeneration

Contemporary Clinical Trials Communications2023-07-048 citations

Reliability of major bleeding events in UK routine data versus clinical trial adjudicated follow-up data

Heart2023-06-038 citations

Effect of low-dose aspirin on urinary 11-dehydro-thromboxane B2 in the ASCEND (A Study of Cardiovascular Events iN Diabetes) randomized controlled trial.

2023-03-043 citations

Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial

European Heart Journal2022-03-2837 citations

Effect of alirocumab on individuals with type 2 diabetes, high triglycerides, and low high-density lipoprotein cholesterol

Cardiovascular Diabetology2020-02-0831 citations

Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study.

2018-12-012 citations

Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus

New England Journal of Medicine2018-08-261133 citations

Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus

New England Journal of Medicine2018-08-26657 citations