Placebo (single dose)

DRUG2 trials

Sponsors

Janssen Research & Development, LLC, J L Marsh

Conditions

HealthyOsteoarthritisPost-traumatic Osteoarthritis

Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42721458 in Healthy Male Participants

CompletedNCT01840501

Janssen Research & Development, LLCHealthy

Start: 2013-04-30End: 2014-04-30Updated: 2014-05-06

Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

TerminatedNCT04589611

J L MarshOsteoarthritis, Post-traumatic Osteoarthritis

Start: 2022-07-20End: 2025-05-01Updated: 2026-07-06