Placebo (matched to pregabalin)

DRUG3 trials

Sponsors

Vertex Pharmaceuticals Incorporated

Conditions

Diabetic Peripheral Neuropathic PainDiabetic Peripheral Neuropathy

Phase 2

Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)

CompletedNCT05660538

Vertex Pharmaceuticals IncorporatedDiabetic Peripheral Neuropathy

Start: 2022-12-20End: 2023-10-25Updated: 2025-07-01

Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy

RecruitingNCT06619860

Vertex Pharmaceuticals IncorporatedDiabetic Peripheral Neuropathic Pain

Start: 2024-10-18End: 2026-05-30Target: 300Updated: 2026-03-16

Phase 3

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

RecruitingNCT06628908

Vertex Pharmaceuticals IncorporatedDiabetic Peripheral Neuropathic Pain

Start: 2024-10-01End: 2027-05-31Target: 1100Updated: 2026-03-31