Placebo (blinded)

DRUG4 trials

Sponsors

Children's Hospital Medical Center, Cincinnati, AstraZeneca, Lexicon Pharmaceuticals, McMaster University

Conditions

Diabetic Peripheral Neuropathic PainEosinophilic GastritisEosinophilic GastroenteritisPrimary Sclerosing Cholangitis (PSC)SclerodermaSystemic SclerosisUlcerative Colitis (UC)

Phase 2

Dupilumab in Eosinophilic Gastritis

CompletedNCT03678545

Children's Hospital Medical Center, CincinnatiEosinophilic Gastritis, Eosinophilic Gastroenteritis

Start: 2021-05-15End: 2024-11-13Updated: 2025-11-04

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)

CompletedNCT06203002

Lexicon PharmaceuticalsDiabetic Peripheral Neuropathic Pain

Start: 2023-11-29End: 2025-02-24Updated: 2025-10-10

Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis

Not yet recruitingNCT07341282

McMaster UniversityPrimary Sclerosing Cholangitis (PSC), Ulcerative Colitis (UC)

Start: 2026-01-31End: 2027-03-31Target: 14Updated: 2026-01-14

Phase 3

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

Active, not recruitingNCT05925803

AstraZenecaScleroderma, Systemic Sclerosis

Start: 2023-11-08End: 2028-04-05Updated: 2026-09-10