Pioglitazone hydrochloride

DRUG12 trials

Conditions

Airflow ObstructionAirway HyperactivityAirway InflammationAsthmaHead and Neck CancerHealthyOral LeukoplakiaPancreatic Cancer

Early Phase 1

Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine

TerminatedNCT00867126

University of Texas Southwestern Medical CenterPancreatic Cancer

Start: 2009-03-02End: 2012-02-29Updated: 2018-11-26

Phase 1

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Pioglitazone Hydrochloride When Given Together to Healthy Subjects

CompletedNCT01088919

Astellas Pharma IncHealthy, Pharmacokinetics of ASP1941

Start: 2009-11-30End: 2009-12-31Updated: 2010-04-16

Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock

CompletedNCT01352182

Children's Hospital Medical Center, CincinnatiSeptic Shock, Severe Sepsis

Start: 2011-10-31End: 2017-01-31Updated: 2020-09-02

A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTS

CompletedNCT02473627

Daiichi SankyoHealthy

Start: 2015-05-31End: 2015-07-31Updated: 2015-11-05

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

CompletedNCT03457597

Corcept TherapeuticsHealthy

Start: 2018-03-06End: 2018-04-28Updated: 2018-05-17

Phase 2

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

CompletedNCT00099021

National Cancer Institute (NCI)Head and Neck Cancer, Oral Leukoplakia

Start: 2003-06-30End: 2008-06-27Updated: 2022-02-11

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

WithdrawnNCT00604578

National Heart, Lung, and Blood Institute (NHLBI)Airflow Obstruction, Airway Hyperactivity, Airway Inflammation +1

Start: 2008-01-04End: 2009-10-30Updated: 2017-07-02

Pioglitazone for Oral Premalignant Lesions

TerminatedNCT00951379

National Cancer Institute (NCI)Oral Leukoplakia

Start: 2010-02-28End: 2014-03-31Updated: 2016-04-06

Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancer

TerminatedNCT01342770

National Cancer Institute (NCI)Stage IA Non-Small Cell Lung Carcinoma, Stage IB Non-Small Cell Lung Carcinoma, Stage IIA Non-Small Cell Lung Carcinoma +2

Start: 2011-04-30End: 2013-02-28Updated: 2017-12-05

Phase 3

Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

CompletedNCT00680745

AstraZenecaType 2 Diabetes

Start: 2008-04-30End: 2010-05-31Updated: 2013-10-14

MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)

CompletedNCT00722371

Merck Sharp & Dohme LLCType 2 Diabetes Mellitus

Start: 2008-09-05End: 2011-03-25Updated: 2017-05-12

Phase 4

Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus Subjects

CompletedNCT01589445

University of DhakaType 2 Diabetes Mellitus

Start: 2008-11-30End: 2010-06-30Updated: 2014-02-28

2024-11-255 citations

A model‐based approach to investigating the relationship between glucose‐insulin dynamics and dapagliflozin treatment effect in patients with type 2 diabetes

Diabetes Obesity and Metabolism2020-12-248 citations

Model‐based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus

Diabetes Obesity and Metabolism2019-02-139 citations

Hypersensitivity Events, Including Potentially Hypersensitivity-Related Skin Events, with Dapagliflozin in Patients with Type 2 Diabetes Mellitus: A Pooled Analysis.

2016-11-0114 citations

The effect of dapagliflozin on renal function in patients with type 2 diabetes

Journal of Nephrology2016-02-1977 citations

Pioglitazone as a candidate chemoprevention agent for lung cancer: A pilot window trial in early stage NSCLC.

Journal of Clinical Oncology2014-05-203 citations

[Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride].

2013-03-253 citations

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial.

2011-10-01301 citations