Pioglitazone 30 Mg Oral Tablet

DRUG3 trials

Sponsors

University of Campinas, Brazil, St. Louis University, Mst.Sumyara Khatun

Conditions

Insulin ResistanceLeukemia, Chronic MyeloidPCOS(Insulin Resistant)Prostate Cancer

Early Phase 1

Insulin Resistance Following ADT for Prostate CA

WithdrawnNCT04658849

St. Louis UniversityInsulin Resistance, Prostate Cancer

Start: 2020-12-02End: 2023-03-29Updated: 2023-05-15

Phase 2

Study of Imatinib Discontinuation in Chronic Myeloid Leukemia With Deep Molecular Response

CompletedNCT02852486

University of Campinas, BrazilLeukemia, Chronic Myeloid

Start: 2016-06-22End: 2024-02-07Updated: 2025-03-30

Unknown Phase

Effect of Pioglitazone vs Metformin on Clinical, Biochemical and Hormonal Parameters of Insulin Resistant PCOS

CompletedNCT07472179

Mst.Sumyara KhatunPCOS(Insulin Resistant)

Start: 2024-08-12End: 2026-02-20Updated: 2026-03-16

Related Papers

Tyrosine Kinase Inhibitor Withdrawal Syndrome in Chronic Myeloid Leukemia Patients Participants of Two Discontinuation Clinical Trials

Blood2023-11-023 citations

Five-Year Follow-up of the Phase I/II Discontinuation Trial of Imatinib after Pioglitazone (EDI-PIO) in Chronic Myeloid Leukemia Patients in Deep Molecular Response

Blood2022-11-153 citations

ESTUDO DE DESCONTINUAÇÃO DE FASE I/II DE IMATINIBE APÓS PIOGLITAZONA (EDI-PIO) EM PACIENTES COM LEUCEMIA MIELOIDE CRÔNICA EM RESPOSTA MOLECULAR PROFUNDA SUSTENTADA – ANÁLISE DE 5 ANOS DE SEGUIMENTO

Hematology Transfusion and Cell Therapy2022-10-01

Metabolic shift of chronic myeloid leukemia patients under imatinib-pioglitazone regimen and discontinuation.

2021-07-243 citations

Duration of Major Molecular Response and Discontinuation in Deep Molecular Response (MR4.5) Were Associated with Longer Treatment-Free Survival after Imatinib Discontinuation - Results from Two Prospective Brazilian Trials

Blood2019-11-136 citations

Pioglitazone Did Not Affect PPAR-Γ, STAT5, HIF2α and CITED2 Gene Expression in Chronic Myeloid Leukemia Patients with Deep Molecular Response

Blood2019-11-136 citations

Pilot Study of Imatinib Discontinuation in Patients with Chronic Myeloid Leukemia with Deep Molecular Response (EDI-PIO) — Evaluation of Pioglitazone in Treatment-Free Remission

Blood2017-12-071 citations