Pictilisib

DRUG3 trials

Sponsors

Genentech, Inc.

Conditions

Breast CancerNon-Small Cell Lung CancerSolid Tumors

Phase 1

A Study of PI3-Kinase Inhibitor GDC-0941 in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole, in Participants With Locally Recurrent or Metastatic Breast Cancer

CompletedNCT00960960

Genentech, Inc.Breast Cancer

Start: 2009-08-31End: 2015-12-31Updated: 2016-12-15

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

TerminatedNCT00996892

Genentech, Inc.Solid Tumors

Start: 2009-11-30End: 2014-03-31Updated: 2016-12-30

Phase 2

Safety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without Pictilisib in Previously Untreated Advanced or Recurrent Non-small Cell Lung Cancer

CompletedNCT01493843

Genentech, Inc.Non-Small Cell Lung Cancer

Start: 2012-01-20End: 2016-03-30Updated: 2017-04-25

Related Papers

A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer.

2018-09-0556 citations