Physostigmine

DRUG9 trials

Conditions

Anesthesia Recovery PeriodAnticholinergics ToxicityCAM-ICU Diagnosed DeliriumCognitive DysfunctionInsulin ResistancePerioperative PeriodPostoperative Nausea and VomitingPostoperative Pain

Early Phase 1

Pharmacological Intervention in Insulin Resistance Targeting Autonomic Nerve Activity

CompletedNCT00689208

AstraZenecaInsulin Resistance

Start: 2007-05-31End: 2008-11-30Target: 12Updated: 2009-03-13

Phase 3

Pilot Study of Physostigmine-Enhanced Opioid Analgesia

CompletedNCT01394445

Medical University of GrazPostoperative Pain

Start: 2011-06-30End: 2011-12-31Updated: 2012-02-22

Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a Surgery

NCT02216266

PD Dr. Bertram SchellerCAM-ICU Diagnosed Delirium, Suspected Delirium After Elective or Emergency Heart Surgery

Start: 2014-04-30End: 2018-12-31Target: 120Updated: 2017-03-10

Phase 4

Treatment of Adolescent Antimuscarinic (Anticholinergic) Toxidrome

CompletedNCT03090620

University of Colorado, DenverAnticholinergics Toxicity

Start: 2017-03-30End: 2020-08-31Updated: 2021-08-23

Unknown Phase

Physostigmine After General Anesthesia

NCT00850850

Bispebjerg HospitalAnesthesia Recovery Period, Postoperative Nausea and Vomiting

Start: 2009-12-31End: 2011-05-31Target: 50Updated: 2010-05-27

The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy

NCT01121497

Rabin Medical CenterCognitive Dysfunction

Start: 2010-07-31End: 2011-07-31Target: 160Updated: 2010-05-12

Phamacological Reversal of Airway Instability During Sedation

CompletedNCT01171118

University of RochesterUpper Airway Obstruction

Start: 2009-08-31End: 2011-08-31Updated: 2015-04-27

Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors

CompletedNCT02008292

Yale UniversitySchizophrenia, Smoking

Start: 2013-09-30End: 2021-12-31Updated: 2023-10-25

Anticholium® Per Se

CompletedNCT03013322

University Hospital HeidelbergPerioperative Period, Sepsis, Shock, Septic

Start: 2015-01-28End: 2017-02-18Updated: 2018-01-29

Related Papers

Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling.

2019-08-063 citations

Effect of physostigmine on recovery from septic shock following intra-abdominal infection – Results from a randomized, double-blind, placebo-controlled, monocentric pilot trial (Anticholium® per Se)

Journal of Critical Care2019-04-0912 citations

Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se).

2017-11-109 citations