Phenylbutyrate

DRUG3 trials

Sponsors

National Cancer Institute (NCI), Brendan Lee

Conditions

Brain NeoplasmsBrain TumorMaple Syrup Urine DiseaseNeuroblastoma

Phase 1

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

CompletedNCT00001565

National Cancer Institute (NCI)Brain Neoplasms, Neuroblastoma

Start: 1996-12-31End: 2000-10-31Target: 35Updated: 2008-03-04

Phase 2

Phenylbutyrate to Treat Children With Progressive or Recurrent Brain Tumors

CompletedNCT00006450

National Cancer Institute (NCI)Brain Tumor

Start: 2000-11-30End: 2002-07-31Target: 120Updated: 2008-03-04

Phenylbutyrate Therapy for Maple Syrup Urine Disease

CompletedNCT01529060

Brendan LeeMaple Syrup Urine Disease

Start: 2013-02-28End: 2017-12-31Updated: 2019-03-19