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Phenoxybenzamine

DRUG6 trials

Sponsors

University of Arkansas, The Cleveland Clinic, Vanderbilt University, University Medical Center Groningen, University of California, Los Angeles

Conditions

Adrenalectomy; StatusAdrenergics Causing Adverse Effects in Therapeutic UseCardiopulmonary BypassCongenital Heart DiseaseCongenital Heart SurgeryOpen-heart SurgeryParagangliomaPheochromocytoma

Phase 2

Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery
CompletedNCT00569855
University of ArkansasCardiopulmonary Bypass, Open-heart Surgery
Start: 2001-02-28End: 2010-08-31Updated: 2011-03-01
Parenteral Phenoxybenzamine During Congenital Heart Disease Surgery
WithdrawnNCT00770705
Vanderbilt UniversityCongenital Heart Disease
Start: 2008-10-31End: 2010-08-31Updated: 2017-05-01

Phase 3

Preoperative Alpha Blockade for Pheochromocytoma
CompletedNCT03176693
University of California, Los AngelesParaganglioma, Pheochromocytoma
Start: 2017-05-05End: 2021-10-10Updated: 2023-11-20

Phase 4

Phenoxybenzamine Versus Doxazosin in PCC Patients
CompletedNCT01379898
University Medical Center GroningenPheochromocytoma
Start: 2011-12-31End: 2018-01-31Updated: 2024-09-19
The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma
RecruitingNCT05702944
Seoul National University HospitalAdrenalectomy; Status, Adrenergics Causing Adverse Effects in Therapeutic Use, Paraganglioma +1
Start: 2023-01-18End: 2027-12-31Target: 24Updated: 2025-06-12

Unknown Phase

Use of Phenoxybenzamine [PBZ] IV to Assist High Flow Low Pressure Perfusion [HFLPP] on Cardio-pulmonary Bypass
TerminatedNCT00620945
The Cleveland ClinicCardiopulmonary Bypass, Congenital Heart Surgery
Start: 2006-06-30End: 2009-02-28Updated: 2017-12-19

Related Papers

Efficacy of α-Blockers on Hemodynamic Control during Pheochromocytoma Resection: A Randomized Controlled Trial
The Journal of Clinical Endocrinology & Metabolism2019-11-12147 citations