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Phase 2

DRUG10 trials

Sponsors

Janssen Research & Development, LLC, Brigham and Women's Hospital, Lycera Corp., Amgen, Quintiles

Conditions

1) Unresected stage IIIB to IVM1c melanomaLymphomaRelapsed or Refractory Hodgkin LymphomaSARS-CoV 2SFSN small nerve fiber neuropathyUlcerative Colitisbile duct cancer Cholangiocarcinomabreast cancer mamma carcinoma

Phase 1

Phase 2

A Phase 2, Multicenter, Open-label, Single-arm Trial to Evaluate the Correlation Between Objective Response Rate and Baseline Intratumoral CD8+ Cell Density in Subjects With Unresected Stage IIIB to IVM1c Melanoma Treated With Talimogene Laherparepvec
Active, not recruitingNL-OMON43786
Amgen1) Unresected stage IIIB to IVM1c melanoma
Start: 2016-06-09Target: 20Updated: 2024-02-28
A MULTICENTER OPEN-LABEL EXTENSION STUDY TO ASSESS THE SAFETY AND TOLERABILITY OF LYC-30937-EC IN SUBJECTS WITH ACTIVE ULCERATIVE COLITIS
Active, not recruitingNL-OMON42876
Lycera Corp.Ulcerative Colitis
Start: 2017-04-19Target: 5Updated: 2024-02-28
Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma, Including Patients with MYC Alterations
NL-OMON46260
Curis, Inc.Lymphoma
Target: 10Updated: 2024-02-28
A Phase 2, Randomized, Double blind, Controlled Study to Evaluate the Safety and Efficacy of VX 440 Combination Therapy in Subjects Aged 12 Years and Older With Cystic Fibrosis
Active, not recruitingNL-OMON45508
Vertex Pharmaceuticalsfibrocystic disease of the pancreas / monogenic disease
Start: 2017-09-25Target: 6Updated: 2024-02-28
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Including FGFR2 Translocations Who Failed Previous Therapy
NL-OMON44339
Quintilesbile duct cancer Cholangiocarcinoma
Target: 4Updated: 2024-02-28
Mesalamine for Colorectal Cancer Prevention Program in Lynch syndrome
NL-OMON44695
Medical University of Viennahereditary colon cancer Lynch syndrome
Target: 170Updated: 2024-02-28
Open-label Phase 2 study evaluating efficacy and safety of SAR566658 treatment in patients with CA6 positive metastatic Triple Negative Breast Cancer
Active, not recruitingNL-OMON46882
Sanofi-aventisbreast cancer mamma carcinoma
Start: 2017-07-26Target: 5Updated: 2024-02-28
VX16-150-102 A Phase 2, Randomized, Double-blind, Placebo-controlled, 6-Week, Parallel-design Study of the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neuropathy
Active, not recruitingNL-OMON46746
Vertex PharmaceuticalsSFSN small nerve fiber neuropathy
Start: 2018-03-05Target: 4Updated: 2024-02-28

Unknown Phase

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