Pharmacokinetic sampling - AZD9291
Sponsors
AstraZeneca
Conditions
Advanced (Inoperable) Non Small Cell Lung CancerAdvanced Non Small Cell Lung CancerHealthy VolunteerNon Small Cell Lung CancerSolid Tumours
Phase 1
Study to Assess the Blood Levels and Safety of AZD9291 in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment
CompletedNCT02161770
Start: 2014-12-22End: 2017-08-22Updated: 2019-03-08
Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer
CompletedNCT02163733
Start: 2014-11-14End: 2023-01-24Updated: 2024-01-22
Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC
CompletedNCT02197234
Start: 2014-12-22End: 2024-06-03Updated: 2025-11-20
Study to Assess the Effect of Rifampicin on Blood Levels and Safety of AZD9291, in Patients With EGFRm+ NSCLC
CompletedNCT02197247
Start: 2014-12-04End: 2021-05-26Updated: 2021-07-12
Drug-Drug Interaction Study With AZD9291 and Omeprazole in Healthy Volunteers
CompletedNCT02224053
Start: 2014-09-30End: 2015-01-31Updated: 2016-06-24
Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer
CompletedNCT02317016
Start: 2015-03-10End: 2018-05-22Updated: 2018-07-31