PF-06882961
Sponsors
Pfizer
Conditions
DiabetesDiabetes Mellitus, Type 2Healthy AdultsHealthy SubjectsObesityOverweightType 2 Diabetes Mellitus
Phase 1
First In Human, Single Escalating Oral Dose Study Of PF-06882961 In Healthy Adult Subjects
CompletedNCT03309241
Start: 2017-10-17End: 2018-03-22Updated: 2018-04-02
4-Week, Multiple-dose, Dose-escalating Study In Patients With Type 2 Diabetes
CompletedNCT03538743
Start: 2018-06-25End: 2019-06-10Updated: 2020-07-01
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus
CompletedNCT04552470
Start: 2020-10-26End: 2021-03-25Updated: 2022-03-11
Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity
CompletedNCT04621227
Start: 2020-12-15End: 2021-05-13Updated: 2023-12-01
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus
CompletedNCT04889157
Start: 2021-07-07End: 2022-02-17Updated: 2024-10-01
STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS
CompletedNCT05093205
Start: 2021-10-25End: 2022-07-06Updated: 2024-08-19
Study to Learn About How the Study Medicines Called PF-07976016 and PF-06882961 Are Taken Up by the Body, and if Either of Them Change How the Body Processes the Other Medicine in Otherwise Healthy Adults With Overweight or Obesity
TerminatedNCT06910839
Start: 2025-03-13End: 2025-05-20Updated: 2025-08-07
Phase 2
A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus
CompletedNCT03985293
Start: 2019-10-15End: 2021-07-07Updated: 2022-06-30
A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY
CompletedNCT04617275
Start: 2021-01-06End: 2021-11-17Updated: 2022-12-08