PF-06650833
Sponsors
Pfizer, Yale University, Giovanni Franchin, M.D, Ph.D
Conditions
Acne InversaCOVID-19COVID-19 PneumoniaHealthyRheumatoid Arthritis
Phase 1
Study to Evaluate Safety and Tolerability of Single Ascending Doses of Multiple Formulations of PF-06650833 in Healthy Subjects Under Fasted and Fed Conditions
CompletedNCT02224651
Start: 2014-09-30End: 2015-06-30Updated: 2015-07-02
Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Oral Pf-06650833 In Healthy Subjects
CompletedNCT02485769
Start: 2015-06-30End: 2016-04-30Updated: 2018-04-19
Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects
CompletedNCT02609139
Start: 2015-11-30End: 2016-02-29Updated: 2016-05-09
Study for MR Formulation of PF-06650833 in Healthy Adult Japanese Subjects
CompletedNCT02936154
Start: 2016-08-31End: 2016-10-31Updated: 2018-10-05
Bioavailability and Food Effect Study of Two Formulations of PF-06650833
CompletedNCT03308110
Start: 2017-09-08End: 2018-01-11Updated: 2019-04-19
A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)
CompletedNCT05064332
Start: 2021-10-08End: 2021-12-16Updated: 2023-10-02
Phase 2
Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate
CompletedNCT02996500
Start: 2016-11-10End: 2018-08-15Updated: 2020-02-27
A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa
CompletedNCT04092452
Start: 2019-12-02End: 2022-01-10Updated: 2023-06-15
TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE
CompletedNCT04413617
Start: 2020-07-29End: 2022-02-07Updated: 2023-04-07
IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)
TerminatedNCT04575610
Start: 2020-11-27End: 2021-10-06Updated: 2021-10-26
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.
NCT04933799
Start: 2021-01-06End: 2022-05-06Target: 68Updated: 2021-06-22