PF-06438179

BIOLOGICAL2 trials

Sponsors

Pfizer

Conditions

HealthyRheumatoid Arthritis

Phase 1

A Pharmacokinetics Study Comparing PF-06438179 and Infliximab in Healthy Volunteers (REFLECTIONS B537-01)

CompletedNCT01844804

Start: 2013-05-31End: 2013-11-30Updated: 2014-01-07

Phase 3

A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).

CompletedNCT02222493

PfizerRheumatoid Arthritis

Start: 2014-08-26End: 2017-06-01Updated: 2018-05-30

Related Papers

Use of multibiomarker disease activity scores in biosimilarity studies for the treatment of patients with rheumatoid arthritis

RMD Open2022-09-011 citations

Long-term Efficacy, Safety, and Immunogenicity of the Infliximab (IFX) Biosimilar, PF-06438179/GP1111, in Patients with Rheumatoid Arthritis After Switching from Reference IFX or Continuing Biosimilar Therapy: Week 54-78 Data From a Randomized, Double-Blind, Phase III Trial.

2020-04-0111 citations

Population pharmacokinetics of PF-06438179/GP1111 (an infliximab biosimilar) and reference infliximab in patients with moderately to severely active rheumatoid arthritis

Expert Opinion on Biological Therapy2019-07-088 citations

Randomised, double-blind, phase III study comparing the infliximab biosimilar, PF-06438179/GP1111, with reference infliximab: efficacy, safety and immunogenicity from week 30 to week 54

RMD Open2019-03-0125 citations

A randomized controlled trial comparing PF-06438179/GP1111 (an infliximab biosimilar) and infliximab reference product for treatment of moderate to severe active rheumatoid arthritis despite methotrexate therapy.

2018-07-2740 citations

A randomized study comparing the pharmacokinetics of the potential biosimilar PF-06438179/GP1111 with Remicade® (infliximab) in healthy subjects (REFLECTIONS B537-01)

Expert Review of Clinical Immunology2018-03-0525 citations

P036. Apoptotic neutrophils ameliorate intestinal inflammation - possible mechanism of granulocyte/monocyte apheresis

Journal of Crohn s and Colitis2015-02-01