PF-04455242

DRUG4 trials

Sponsors

Pfizer

Conditions

Bipolar DepressionBipolar DisorderDepressionHealthy

Phase 1

A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers

CompletedNCT00938301

PfizerBipolar Depression

Start: 2009-04-30End: 2009-07-31Updated: 2009-10-16

A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)

TerminatedNCT00939887

PfizerBipolar Disorder, Depression

Start: 2009-09-30End: 2009-12-31Updated: 2010-02-08

A Multiple Dose Study To Determine Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Healthy Adult Subjects

CompletedNCT00956956

Start: 2009-09-30End: 2009-12-31Updated: 2010-01-07

Proof Of Mechanism Study To Determine Efficacy Of PF-04455242 In Blocking Spiradoline (PF-00345768) Stimulated Prolactin Release

CompletedNCT00988949

PfizerBipolar Depression

Start: 2009-11-30End: 2009-12-31Updated: 2010-01-07