Personalized neoantigen DNA vaccine

BIOLOGICAL3 trials

Sponsors

Washington University School of Medicine

Conditions

Cancer of the PancreasPancreas CancerPancreatic CancerPediatric Recurrent Central Nervous System TumorsUnmethylated Glioblastoma

Phase 1

Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

TerminatedNCT03122106

Washington University School of MedicineCancer of the Pancreas, Pancreas Cancer, Pancreatic Cancer

Start: 2018-01-05End: 2022-08-13Updated: 2023-10-10

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

RecruitingNCT03988283

Washington University School of MedicinePediatric Recurrent Central Nervous System Tumors

Start: 2024-10-02End: 2031-02-28Target: 7Updated: 2025-11-25

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Active, not recruitingNCT05743595

Washington University School of MedicineUnmethylated Glioblastoma

Start: 2023-10-27End: 2029-03-09Updated: 2026-03-11