Pentoxifylline 400mg plus chemotherapy

DRUG2 trials

Sponsors

Mansoura University, Tanta University

Conditions

Breast CancerBreast Cancer FemaleBreast Cancer PatientsDoxorubicinDoxorubicin Induced CardiotoxicityNeoadjuvant TherapyTaxane-induced Peripheral Neuropathy

Phase 2

Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer

CompletedNCT06186700

Mansoura UniversityBreast Cancer Female, Breast Cancer Patients, Doxorubicin +2

Start: 2023-12-25End: 2024-12-01Updated: 2025-07-28

Clinical Study to Evaluate The Cardioprotective Effect of Pentoxifylline Against Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

RecruitingNCT07137793

Tanta UniversityBreast Cancer, Doxorubicin Induced Cardiotoxicity

Start: 2025-05-25End: 2026-12-31Target: 46Updated: 2025-08-22

Related Papers

Editorial: Advancement of chemotherapy in breast cancer: predictive markers, resistance mechanism and therapeutic strategies

Frontiers in Oncology2026-07-03

Assessing the efficacy and safety of pentoxifylline in preventing chemotherapy-induced peripheral neuropathy and mucositis in breast cancer patients.

2025-10-14