Pentamidine

DRUG11 trials

Conditions

African TrypanosomiasisColorectal CancerDiabetes Mellitus, Insulin-DependentHIV-infection/AidsHematologic MalignancyHodgkin LymphomaKidney DiseaseKidney Transplantation

Phase 1

Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults

CompletedNCT00078559

University of Wisconsin, MadisonKidney Disease, Kidney Transplantation

Start: 2003-11-30End: 2010-02-28Updated: 2018-06-29

A Safety Study of Pentamidine in Patients With Metastatic Colon Cancer Undergoing Standard Chemotherapy as Second-line and/or Third-line Treatment

CompletedNCT00809796

Oncozyme Pharma Inc.Colorectal Cancer

Start: 2008-03-31End: 2011-06-30Target: 15Updated: 2011-06-28

A Safety Study Using Pentamidine in Patients With Pancreatic Cancer Undergoing Standard Therapy

CompletedNCT00810953

Oncozyme Pharma Inc.Pancreatic Cancer

Start: 2009-01-31End: 2011-06-30Updated: 2011-06-28

Pentamidine + Salvage Chemo for Relapsed/Refractory Classical Hodgkin Lymphoma

CompletedNCT03730363

Reinhold MunkerHodgkin Lymphoma, Refractory Hodgkin Lymphoma

Start: 2018-12-19End: 2019-05-23Updated: 2021-07-07

Phase 2

Islet Transplantation for Type 1 Diabetes

CompletedNCT00014911

National Institute of Allergy and Infectious Diseases (NIAID)Diabetes Mellitus, Insulin-Dependent

Start: 2001-04-30End: 2010-08-31Updated: 2017-03-15

Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma

CompletedNCT00002524

M.D. Anderson Cancer CenterLymphoma

Start: 1993-06-30End: 2005-10-31Updated: 2012-07-30

0794GCC: Pentamidine in Treating Patients With Relapsed or Refractory Melanoma

TerminatedNCT00729807

University of Maryland, BaltimoreMelanoma (Skin)

Start: 2008-07-31End: 2012-11-30Updated: 2019-08-16

Trial of DB289 for the Treatment of Stage I African Trypanosomiasis

CompletedNCT00803933

Immtech Pharmaceuticals, IncAfrican Trypanosomiasis

Start: 2003-02-28End: 2005-06-30Updated: 2008-12-08

Phase 3

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

CompletedNCT01360762

Institute of Tropical Medicine, BelgiumHIV-infection/Aids, Visceral Leishmaniosis

Start: 2011-11-30End: 2015-11-30Updated: 2019-02-15

Phase 4

Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)

Not yet recruitingNCT07357103

McGill University Health Centre/Research Institute of the McGill University Health CentrePneumocystis, Pneumocystis Carinii Infection, Pneumocystis Carinii; Infection, Resulting From HIV Disease +5

Start: 2026-03-01End: 2029-09-01Target: 416Updated: 2026-01-21

Unknown Phase

Intravenous Pentamidine for Pneumocystis Jirovecii Pneumonia

CompletedNCT02669706

University of Illinois at ChicagoHematologic Malignancy

Start: 2015-03-31End: 2016-06-30Updated: 2016-06-30

Related Papers

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation.

2018-04-136 citations

A prospective study of intravenous pentamidine for PJP prophylaxis in adult patients undergoing intensive chemotherapy or hematopoietic stem cell transplant.

2017-12-2111 citations

Long-term Clinical Outcomes in Visceral Leishmaniasis/Human Immunodeficiency Virus–Coinfected Patients During and After Pentamidine Secondary Prophylaxis in Ethiopia: A Single-Arm Clinical Trial

Clinical Infectious Diseases2017-09-1230 citations