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Pemetrexed injection

DRUG5 trials

Sponsors

Shanghai JMT-Bio Inc., Xiangya Hospital of Central South University, Shanghai Junshi Bioscience Co., Ltd., Guangzhou JOYO Pharma Co., Ltd, Shanghai Huaota Biopharmaceutical Co., Ltd.

Conditions

Leptomeningeal MetastasisLocal Advanced or Metastatic NSCLCLung CancerNon Small Cell Lung CancerNon Squamous Non-small Cell Lung CancerNon-small Cell Lung Cancer

Phase 2

JS207Combined With Chemotherapy in First-line Treatment of Advanced NSCLC
RecruitingNCT06969027
Shanghai Junshi Bioscience Co., Ltd.Non-small Cell Lung Cancer
Start: 2025-06-19End: 2027-12-31Target: 84Updated: 2025-07-04

Phase 3

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations
Not yet recruitingNCT06380348
Shanghai JMT-Bio Inc.Local Advanced or Metastatic NSCLC
Start: 2024-04-26End: 2028-03-26Target: 398Updated: 2024-04-23
JYP0322 Versus Platinum Based Doublet Chemotherapy in ROS1 Positive Patients Previously Treated With ROS1-TKIs.
Not yet recruitingNCT07154368
Guangzhou JOYO Pharma Co., LtdNon Small Cell Lung Cancer
Start: 2025-09-23End: 2029-12-31Target: 207Updated: 2025-09-19
Phase III Clinical Study of HB0025 Combined With Chemotherapy Versus Tislelizumab Combined With Chemotherapy as First-Line Treatment for Advanced Nonsquamous Non-Small Cell Lung Cancer
Not yet recruitingNCT07383116
Shanghai Huaota Biopharmaceutical Co., Ltd.Non Squamous Non-small Cell Lung Cancer
Start: 2026-01-15End: 2028-04-10Target: 500Updated: 2026-02-03

Unknown Phase

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir
RecruitingNCT06399926
Xiangya Hospital of Central South UniversityLeptomeningeal Metastasis, Lung Cancer
Start: 2023-10-30End: 2027-06-30Target: 64Updated: 2024-05-06