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Pembrolizumab alone
DRUG
2 trials
Sponsors
Prof. Dr. med. Dirk Schadendorf
, National Cancer Centre, Singapore
Conditions
Colorectal Cancer
Malignant Melanoma
Phase 1
Encorafenib + Binimetinib + Pembrolizumab in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma
Completed
NCT02902042
Prof. Dr. med. Dirk Schadendorf
Malignant Melanoma
Start: 2018-04-24
End: 2020-11-30
Updated: 2021-02-16
Phase 2
Window of Opportunity Study in Colorectal Cancer
Completed
NCT03984578
National Cancer Centre, Singapore
Colorectal Cancer
Start: 2019-06-12
End: 2025-02-28
Updated: 2025-11-18
Related Papers
Encorafenib, binimetinib plus pembrolizumab triplet therapy in patients with advanced BRAF<sup>V600</sup> mutant melanoma: safety and tolerability results from the phase I IMMU-TARGET trial.
2021-10-13
17 citations
Triplet therapy with pembrolizumab (PEM), encorafenib (ENC) and binimetinib (BIN) in advanced, BRAF V600 mutant melanoma: Final results from the dose-finding phase I part of the IMMU-Target trial.
Journal of Clinical Oncology
2021-05-20
4 citations