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Pemazyre 4.5 mg tablets

DRUG10 trials

Sponsors

Region Skane, Incyte Corp., Incyte Corp., Incyte Corp., Oslo University Hospital HF, Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

Conditions

23 fusion/rearrangement or activating mutationAdvanced CancerAdvanced solid tumorCancerCholangiocarcinomaDedifferentiated LiposarcomaEndometrial cancer

Phase 2

INCB 54828-801: An Open-Label, Multicenter, Rollover Study to Provide Continued Treatment for Participants With Advanced Malignancies Previously Enrolled in Studies of Pemigatinib
CompletedCTIS2023-503406-36-00
Incyte Corp., Incyte Corp.Male and female participants at least 18 years of age who are actively receiving treatment with pemigatinib under a parent protocol and receiving clinical benefit and who do not have access to pemigatinib outside of a clinical trial
Start: 2021-12-13End: 2023-05-11Target: 4Updated: 2023-06-09
PERELI - A phase 2, open label study of PEmigatinib and REtifanlimab in advanced dedifferentiated Liposarcoma
RecruitingCTIS2022-501993-21-00
Region SkaneDedifferentiated Liposarcoma
Start: 2024-06-20Target: 33Updated: 2025-10-15
INCMGA 0012-204: An Umbrella Study of INCMGA00012 Alone and in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-Based Chemotherapy (POD1UM-204)
Active, not recruitingCTIS2022-502600-79-00
Incyte Corp.Endometrial cancer
Start: 2021-03-16Target: 88Updated: 2025-09-24
A Dutch National Study on behalf of the Center for Personalized Cancer Treatment (CPCT) to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to determine the Potential Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile: The Drug Rediscovery Protocol (DRUP trial)
RecruitingCTIS2023-509152-33-00
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis StichtingAdvanced solid tumor, Multiple myeloma, Non-Hodgkin lymphoma +1
Start: 2016-07-25Target: 3000Updated: 2025-12-19
ProTarget - A Danish Nationwide Clinical Trial on Targeted Anti‐Cancer Treatment based on Genomic Profiling
RecruitingCTIS2023-510527-29-00
RigshospitaletCancer
Start: 2020-09-01Target: 600Updated: 2025-04-25
PEARLDIFER - A Phase II study of pemigatinib after curative local therapy in locally advanced intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 fusions/rearrangements
CompletedCTIS2024-512018-16-00
Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbHlocally advanced intrahepatic cholangiocarcinoma (iCCA) with FGFR2 fusions/rearrangements
Start: 2022-11-11End: 2025-03-27Target: 20Updated: 2025-03-18
Improving public cancer care by implementing precision medicine in Norway A multi-cohort phase 2 treatment clinical study investigating efficacy of approved drugs outside indication in patients with advanced cancer. IMPRESS-Norway
RecruitingCTIS2023-507894-16-00
Oslo University Hospital HFCancer
Start: 2021-04-01Target: 6000Updated: 2026-01-22
AcSé pemigatinib: Phase II trial evaluating the efficacy of pemigatinib in patients with recurrent and/or metastatic solid tumor harboring a FGFR alteration
RecruitingCTIS2024-512729-10-00
Unicancer2, 3 fusion/rearrangement or activating mutation, outside of the approved indications for any selective FGFR inhibitor in France +1
Start: 2025-03-27Target: 40Updated: 2025-06-10
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs to determine the Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile
Not yet recruitingCTIS2024-517478-68-01
HUS-YhtymaeAdvanced Cancer
Target: 250Updated: 2024-11-06

Phase 3

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