peginterferon beta-1a
Sponsors
Novartis Pharma AG, Centre Hospitalier Universitaire De Montpellier, Centre Hospitalier Universitaire De Rennes, Biogen, Food and Drug Administration (FDA)
Conditions
Covid19Exposure During PregnancyHealthyHealthy SubjectsInterferonMultiple SclerosisMultiple Sclerosis, Relapsing-RemittingMultiple sclerosis
Phase 1
Pharmacokinetic Study of Peginterferon Beta-1a in Japanese and Caucasian Adult Healthy Participants.
CompletedNCT01978652
Start: 2013-12-31End: 2014-02-28Updated: 2015-01-09
Study to Evaluate the Pharmacokinetic Profiles of BIIB017 (Peginterferon Beta-1a) and Rebif® (Interferon Beta-1a) in Healthy Volunteers
CompletedNCT02269930
Start: 2014-10-31End: 2014-12-31Updated: 2015-02-02
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interferon Beta-1A Products
CompletedNCT04183491
Start: 2020-02-28End: 2021-01-26Updated: 2024-04-22
Phase 3
Long-Term Safety and Efficacy Study of Peginterferon Beta-1a
CompletedNCT01332019
Start: 2011-04-30End: 2015-10-31Updated: 2017-01-13
Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric Participants
TerminatedNCT03870763
Start: 2019-03-19End: 2022-07-21Updated: 2023-06-15
The Containing Coronavirus Disease 19 (COVID-19) Trial
CompletedNCT04552379
Start: 2020-12-01End: 2021-06-30Updated: 2021-09-10
An Open-Label, Rater-Blind, Randomized, Multi-Center, Parallel-Arm, Active-Comparator Study to Assess the Efficacy and Tolerability of Ofatumumab 20mg SC monthly vs. First Line DMT - physician’s choice in the treatment of newly diagnosed RMS (STHENOS)
CompletedCTIS2023-507431-37-00
Start: 2021-07-23End: 2025-11-04Target: 186Updated: 2025-06-02
STOP-I-SEP_Disease modifying therapies withdrawal in inactive Secondary Progressive Multiple Sclerosis patients older than 50 years
Active, not recruitingCTIS2024-516628-32-00
Start: 2019-01-24Target: 250Updated: 2025-12-12
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
Not yet recruitingCTIS2024-513292-40-00
Target: 250Updated: 2025-04-28
Phase 4
Brimonidine Tartrate for the Treatment of Injection Related Erythema
WithdrawnNCT02568111
Start: 2016-02-29End: 2016-08-31Updated: 2016-04-25
Plegridy Satisfaction Study in Participants
CompletedNCT02587065
Start: 2016-02-03End: 2017-12-21Updated: 2023-08-31
Evaluate Safety/Tolerability in Portuguese Participants With RRMS Transitioning From Current Therapy
CompletedNCT03177083
Start: 2017-01-30End: 2020-10-26Updated: 2020-11-25
Unknown Phase
Biogen Multiple Sclerosis Pregnancy Exposure Registry
CompletedNCT01911767
Start: 2013-10-30End: 2022-02-10Updated: 2022-06-21
Plegridy Observational Program
CompletedNCT02230969
Start: 2014-11-12End: 2022-01-20Updated: 2022-09-26
A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies
RecruitingNCT05688436
Start: 2021-09-24End: 2031-01-17Target: 1178Updated: 2025-10-17