PCV20
Sponsors
Merck Sharp & Dohme LLC, Medical University of Vienna, GlaxoSmithKline, M.D. Anderson Cancer Center, LiteVax BV
Conditions
COVID-19LymphomaPneumococcal InfectionPneumococcal InfectionsPneumococcal VaccinesPneumonia, BacterialRespiratory Syncytial Virus InfectionsVaccine Reaction
Phase 1
Safety and Immunogenicity of PCV-LITE, a Low-dose of Pneumococcal Conjugate Vaccine With LiteVax Adjuvant
Not yet recruitingNCT06986239
Start: 2025-07-01End: 2026-07-01Target: 80Updated: 2025-05-22
A Trial to Evaluate the Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults 50 To 64 Years of Age
Active, not recruitingNCT07105722
Start: 2025-08-12End: 2026-06-09Updated: 2025-12-24
A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months of Age Receiving a Single Booster Dose
Not yet recruitingNCT07406334
Start: 2026-05-15End: 2027-02-22Target: 45Updated: 2026-02-12
A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose Primary Dosing Series Followed by a Booster Dose at 12 to 15 Months of Age
Not yet recruitingNCT07406347
Start: 2026-07-10End: 2028-04-03Target: 60Updated: 2026-02-12
Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years
Not yet recruitingNCT07428759
Start: 2026-03-10End: 2026-12-24Target: 120Updated: 2026-02-24
Phase 3
Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults (V116-003, STRIDE-3)
CompletedNCT05425732
Start: 2022-07-13End: 2023-05-18Updated: 2024-10-26
Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults
CompletedNCT05879107
Start: 2023-05-26End: 2024-05-07Updated: 2025-05-18
Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49
Active, not recruitingNCT07284654
Start: 2025-12-01End: 2027-01-01Updated: 2026-03-31
Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination
RecruitingNCT07425392
Start: 2026-02-09End: 2027-03-01Target: 720Updated: 2026-03-18
Phase 4
Concomitant Administration of the Novavax Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years
NCT05767606
Start: 2023-03-31End: 2023-08-31Target: 256Updated: 2023-03-15
Immunogenicity and Clinical Efficacy of 20-valent Pneumococcal Conjugate Vaccine (PCV20) in Lymphoma Survivors After Treatment With Anti-CD20 Therapy
Active, not recruitingNCT06049134
Start: 2023-10-06End: 2027-12-01Updated: 2026-03-09