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Panitumumab-IRDye800

DRUG9 trials

Sponsors

George Poultsides, Eben Rosenthal, Stanford University, Andrei Iagaru, University of Alabama at Birmingham

Conditions

Acoustic NeuromaBrain CancerBrain TumorCarcinoma of the Head and NeckGlioblastomaHead and Neck CancerHead and Neck Squamous Cell CarcinomaLung Carcinoma

Early Phase 1

Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Not yet recruitingNCT07493447
Eben RosenthalAcoustic Neuroma, Brain Cancer, Glioblastoma +2
Start: 2026-05-02End: 2031-06-02Target: 30Updated: 2026-03-25

Phase 1

Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
RecruitingNCT03384238
George PoultsidesPancreatic Adenocarcinoma
Start: 2018-02-07End: 2027-09-01Target: 27Updated: 2026-03-17
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
RecruitingNCT03510208
Stanford UniversityMalignant Brain Neoplasm, Malignant Glioma
Start: 2018-05-16End: 2026-05-01Target: 46Updated: 2026-02-09
Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery
RecruitingNCT03582124
Stanford UniversityLung Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage IVA Lung Cancer AJCC v8 +2
Start: 2018-07-19End: 2026-09-01Target: 30Updated: 2026-02-10
Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer
CompletedNCT03733210
Andrei IagaruCarcinoma of the Head and Neck, Squamous Cell Carcinoma of the Head and Neck
Start: 2019-01-07End: 2021-08-09Updated: 2023-05-19
Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
RecruitingNCT04085887
Stanford UniversityBrain Tumor
Start: 2026-04-01End: 2028-12-01Target: 12Updated: 2026-03-20
Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer
RecruitingNCT05945875
Vanderbilt-Ingram Cancer CenterHead and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Start: 2023-10-03End: 2028-12-31Target: 40Updated: 2025-10-03

Phase 2

Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer
CompletedNCT03405142
Eben RosenthalHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Start: 2019-08-01End: 2021-04-27Updated: 2022-11-10
Phase II Panitumumab-IRDye800 in Head & Neck Cancer
RecruitingNCT04511078
University of Alabama at BirminghamHead and Neck Cancer
Start: 2021-04-02End: 2030-12-31Target: 25Updated: 2025-12-24

Related Papers

Intraoperative Molecular Imaging Can Detect Large Nerve Perineural Invasion: A Case Report.
2026-01-07
Tumour-specific fluorescence-guided surgery for pancreatic cancer using panitumumab-IRDye800CW: a phase 1 single-centre, open-label, single-arm, dose-escalation study.
2020-05-1475 citations