Pancrelipase

DRUG13 trials

Sponsors

Ohdan Hideki, Digestive Care, Inc., Mylan Inc., American Academy of Family Physicians, University of Colorado, Denver

Conditions

Cases of adjuvant chemotherapy administered after gastrectomy for Stage2 and 3 gastric cancer Gastric CancerCeliac DiseaseChronic PancreatitisCystic FibrosisDigestive System DiseasesExocrine Pancreatic InsufficiencyExocrine Pancreatic Insufficiency (EPI)Irritable Bowel Syndrome

Phase 1

PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

TerminatedNCT02985801

Massimo Raimondo, M.D.Pancreatic Cancer, Pancreatic Enzyme Abnormality, Pancreatic Insufficiency

Start: 2016-12-31End: 2019-04-30Updated: 2021-03-15

Phase 2

Trial of Pancreatic Enzyme Supplements (Pancrelipase) for Treating Pain in Patients With Chronic Pancreatitis

WithdrawnNCT02706236

Dartmouth-Hitchcock Medical CenterPancreatitis

Start: 2016-04-30End: 2018-12-31Updated: 2018-02-27

Study of Pancreatic Enzyme Replacement on Completion of Adjuvant Chemotherapy for Resected Pancreatic Adenocarcinoma

TerminatedNCT03469258

Dana-Farber Cancer InstitutePancreatic Cancer

Start: 2018-04-13End: 2019-10-01Updated: 2020-08-03

Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency

Active, not recruitingNCT04098237

Andrew Hendifar, MDPancreatic Adenocarcinoma

Start: 2020-12-17End: 2027-01-01Updated: 2026-01-23

The efficacy and safety of pancrelipase in patients undergoing adjuvant chemotherapy after gastrectomy: A multicenter, prospective, open-label study.

RecruitingJPRN-jRCT1061250077

Ohdan HidekiCases of adjuvant chemotherapy administered after gastrectomy for Stage2 and 3 gastric cancer Gastric Cancer

Start: 2026-05-18Target: 100Updated: 2026-06-29

Phase 4

Intraduodenal Aspiration Study to Assess the Bioavailability of Oral Pancrecarb® Compared to Placebo Control

TerminatedNCT00744250

Digestive Care, Inc.Chronic Pancreatitis, Cystic Fibrosis, Exocrine Pancreatic Insufficiency

Start: 2008-08-31End: 2010-05-31Updated: 2013-02-22

Irritable Bowel Syndrome Evaluation and Treatment in Primary Care

CompletedNCT01641341

American Academy of Family PhysiciansIrritable Bowel Syndrome

Start: 2010-11-30End: 2012-03-31Updated: 2019-01-23

Pancreatic Enzyme Supplementation for Celiac Disease

TerminatedNCT02475369

Beth Israel Deaconess Medical CenterCeliac Disease

Start: 2015-05-31End: 2019-12-31Updated: 2021-05-12

A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)

TerminatedNCT03859869

AbbVieExocrine Pancreatic Insufficiency (EPI)

Start: 2020-02-25End: 2022-03-23Updated: 2023-06-05

A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

CompletedNCT03924947

AbbVieCystic Fibrosis

Start: 2019-10-23End: 2022-07-11Updated: 2023-09-28

Unknown Phase

Bioavailability of Pancreatic Enzymes in the Human Upper Intestine (Duodenum and Jejunum)

TerminatedNCT00749099

Digestive Care, Inc.Exocrine Pancreatic Insufficiency

Start: 2007-04-30End: 2010-09-30Updated: 2013-02-22

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

CompletedNCT01427712

Mylan Inc.Cystic Fibrosis, Digestive System Diseases, Exocrine Pancreatic Insufficiency +1

Start: 2011-08-31End: 2018-03-31Updated: 2022-06-10

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

CompletedNCT02372383

University of Colorado, DenverCystic Fibrosis

Start: 2014-10-31End: 2016-06-30Updated: 2021-02-11

Related Papers

The effect of cachexia and anti-cancer therapies on GDF-15 levels in patients with pancreatic adenocarcinoma.

Journal of Clinical Oncology2025-01-271 citations

Pancreatic-enzyme replacement therapy with pancrelipase plus chemotherapy for patients with pancreatic adenocarcinoma with cachexia and exocrine pancreatic insufficiency (PANCAX-3).

Journal of Clinical Oncology2024-06-01

Pancreatic enzyme supplementation versus placebo for improvement of gastrointestinal symptoms in non-responsive celiac disease: A cross-over randomized controlled trial

Frontiers in Medicine2023-01-047 citations

Pharmacokinetics of oral antimycobacterials and dosing guidance for Mycobacterium avium complex treatment in cystic fibrosis.

2021-05-216 citations