Palliative Radiation Therapy

RADIATION15 trials

Sponsors

Cancer Trials Ireland, Sunnybrook Health Sciences Centre, Eastern Cooperative Oncology Group, Fred Hutchinson Cancer Center, Maisonneuve-Rosemont Hospital

Conditions

Advanced CancerBreast CancerExtensive Stage Lung Small Cell CarcinomaGlioblastomaHead and Neck NeoplasmsHepatocellular CarcinomaImmunotherapyLiver Metastases

Phase 1

NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy

CompletedNCT02319824

Fred Hutchinson Cancer CenterSarcoma

Start: 2015-01-31Updated: 2017-07-05

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

Active, not recruitingNCT02959463

M.D. Anderson Cancer CenterPleural Malignant Mesothelioma

Start: 2017-05-01End: 2028-12-31Updated: 2026-03-06

Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer

RecruitingNCT05244239

Emory UniversityExtensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8

Start: 2022-07-27End: 2027-07-28Target: 22Updated: 2025-10-31

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

RecruitingNCT06306638

Roswell Park Cancer InstituteMalignant Solid Neoplasm

Start: 2024-10-01End: 2029-10-01Target: 53Updated: 2025-11-25

Phase 2

Aprepitant and Granisetron for the Prophylaxis of Radiation Induced Nausea and Vomiting - A Pilot Study

TerminatedNCT01183481

Sunnybrook Health Sciences CentreNausea, Vomiting

Start: 2011-01-31End: 2013-03-31Updated: 2019-10-09

Palliative Radiotherapy Protocol in Head and Neck Cancer

CompletedNCT02460471

Maisonneuve-Rosemont HospitalHead and Neck Neoplasms, Quality of Life

Start: 2011-06-30End: 2015-04-30Updated: 2015-06-02

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

RecruitingNCT04068649

Roswell Park Cancer InstituteMetastatic Malignant Neoplasm

Start: 2019-11-18End: 2027-11-18Target: 1500Updated: 2025-04-25

Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care

RecruitingNCT06556550

National Medical Research Radiological Centre of the Ministry of Health of RussiaOligometastatic Disease

Start: 2024-05-31End: 2029-12-31Target: 100Updated: 2024-08-16

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

RecruitingNCT06660407

Mayo ClinicLung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8

Start: 2024-11-14End: 2027-01-10Target: 20Updated: 2026-03-16

Unknown Phase

Palliative 3-Dimensional Conformal Radiation Therapy in Reducing Radiation Side Effects in Patients With Lung Cancer. ICORG 06-34

CompletedNCT01176487

Cancer Trials IrelandLung Cancer

Start: 2010-06-30End: 2016-03-31Target: 40Updated: 2016-03-31

Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer

CompletedNCT01242800

Eastern Cooperative Oncology GroupBreast Cancer, Stage IV Breast Cancer

Start: 2011-05-16End: 2022-12-21Updated: 2023-06-29

Study of Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases

CompletedNCT02511522

Canadian Cancer Trials GroupHepatocellular Carcinoma, Liver Metastases

Start: 2015-12-11End: 2024-10-02Updated: 2024-10-23

Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme

CompletedNCT02575027

Jonsson Comprehensive Cancer CenterGlioblastoma, Recurrent Brain Neoplasm

Start: 2014-11-12End: 2018-06-20Updated: 2019-02-28

Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis

CompletedNCT02699697

Wake Forest University Health SciencesMalignant Neoplasm, Metastatic Malignant Neoplasm in the Bone, Pain

Start: 2016-05-31End: 2025-03-20Updated: 2025-12-11

Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy

CompletedNCT03042156

University Health Network, TorontoAdvanced Cancer, Immunotherapy, Palliative +1

Start: 2017-01-10End: 2025-04-30Updated: 2026-03-04

Related Papers

Palliative radiotherapy versus best supportive care in patients with painful hepatic cancer (CCTG HE1): a multicentre, open-label, randomised, controlled, phase 3 study.

2024-09-0516 citations

Canadian Cancer Trials Group HE.1: A phase III study of palliative radiotherapy for symptomatic hepatocellular carcinoma and liver metastases.

Journal of Clinical Oncology2023-01-249 citations

A randomized phase III trial of systemic therapy plus early local therapy versus systemic therapy alone in women with de novo stage IV breast cancer: A trial of the ECOG-ACRIN Research Group (E2108).

Journal of Clinical Oncology2020-06-01121 citations

Zoledronic acid in the management of mesothelioma - a feasibility study (Zol-A Trial): study protocol for a randomised controlled trial.

2018-08-294 citations

Cancer Trials Ireland (ICORG) 06-34: A multi-centre clinical trial using three-dimensional conformal radiation therapy to reduce the toxicity of palliative radiation for lung cancer.

2018-03-1315 citations