palifosfamide-tris

DRUG3 trials

Sponsors

Alaunos Therapeutics

Conditions

Advanced Solid TumorsCancerExtensive-Stage Small Cell Lung CancerMalignancyNon Small Cell Lung CancerOsteosarcomaOvarian CancerSmall Cell Lung Cancer

Phase 1

Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies

Alaunos TherapeuticsCancer, Malignancy, Non Small Cell Lung Cancer +5

Start: 2010-11-30End: 2012-12-31Target: 12Updated: 2012-07-18

Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjects With Advanced Solid Tumors

Alaunos TherapeuticsAdvanced Solid Tumors

Start: 2011-06-30End: 2013-09-30Target: 24Updated: 2013-07-18

Phase 3

Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer (The MATISSE Study)

Alaunos TherapeuticsExtensive-Stage Small Cell Lung Cancer

Start: 2012-05-31End: 2015-06-30Target: 548Updated: 2013-05-21

Related Papers

Results from a randomized study of carboplatin and etoposide (CE) with or without palifosfamide (Pa) in extensive stage small cell lung cancer (ES-SCLC): The MATISSE study.

Journal of Clinical Oncology2015-05-203 citations