Padcev 20 mg powder for concentrate for solution for infusion
Sponsors
Seagen Inc., Astrazeneca AB, Grupo Espanol Multidisciplinar De Melanoma, Grupo Espanol De Tumores Neuroendocrinos, Summit Therapeutics Inc.
Conditions
Advanced MelanomaBladder CancerLocally Advanced or Metastatic Urothelial CarcinomaNeuroendocrine Carcinoma / G3 Neuroendocrine TumoursUrothelial cancer
Phase 2
C5701002/SGN22E-002 - A study of enfortumab vedotin (ASG-22CE) as monotherapy or in combination with other anticancer therapies for the treatment of urothelial cancer
Active, not recruitingCTIS2023-503391-24-00
Start: 2021-05-26Target: 7Updated: 2026-01-19
Multicenter, open label, single arm, phase II study to assess the efficay and safety of enfortumab-vedotin (EV) as a single agent in patients with advanced Neuroendocrine Carcinomas (NEC) refractory or ineligible to platinum-containing chemotherapy
RecruitingCTIS2024-515511-21-00
Start: 2025-03-13Target: 63Updated: 2025-10-29
A Phase II, Open-Label, Multicenter, Non-Randomized Study Of The Efficacy And Safety Of Enfortumab Vedotin In Combination With Pembrolizumab Previously Treated
Advanced Melanoma
RecruitingCTIS2024-514163-26-00
Start: 2025-06-09Target: 60Updated: 2025-03-18
A Randomized Phase 2/3 Study of Ivonescimab in Combination with Enfortumab Vedotin vs Pembrolizumab in Combination with Enfortumab Vedotin in Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma (HARMONi GU1)
Not yet recruitingCTIS2026-525831-17-00
Target: 15Updated: 2026-09-21