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Paclitaxel Ribosepharm 6 mg/ml Konzentrat zur Herstellung einer Infusionslösung

DRUG8 trials

Sponsors

Immunogen Inc., Gilead Sciences Inc., Summit Therapeutics Sub Inc., Verastem Inc., Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

Conditions

Advanced Non-Small Cell Lung CancerHER2-expressing endometrial cancer (IHC 3+/2+)Locoregional Recurrence of Squamous Cell Carcinoma of the Head and Neck (HNSCC)Metastatic Non-small Cell Lung CancerMetastatic Squamous Non-small Cell Lung CancerPlatinum-sensitive epithelial ovarianRecurrent Low-Grade Serous Ovarian Cancer (LGSOC)advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junctions

Phase 2

Phase 3

2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
RecruitingCTIS2022-501606-35-01
Immunogen Inc.fallopian tube, or primary peritoneal cancers, Platinum-sensitive epithelial ovarian
Start: 2024-02-21Target: 110Updated: 2026-01-21
A Randomized, Controlled, Multiregional Phase 3 Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemotherapy for the First-line Treatment of Metastatic Squamous Non-small Cell Lung Cancer
WithdrawnCTIS2023-504989-37-00
Summit Therapeutics Sub Inc.Metastatic Squamous Non-small Cell Lung Cancer
Target: 135Updated: 2024-01-08
A Phase 3, Randomized, Open-Label Study of Combination Therapy with Avutometinib plus Defactinib Versus Investigator’s Choice of Treatment in Patients with Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) (RAMP301)
RecruitingCTIS2023-508204-38-00
Verastem Inc.Recurrent Low-Grade Serous Ovarian Cancer (LGSOC)
Start: 2024-07-02Target: 183Updated: 2026-01-06
A Randomized, Double-blind, Multiregional Phase 3 Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemotherapy for the First-line Treatment of Metastatic Non-small Cell Lung Cancer (HARMONi-3)
RecruitingCTIS2024-513087-26-00
Summit Therapeutics Inc.Metastatic Non-small Cell Lung Cancer
Start: 2024-09-10Target: 661Updated: 2026-01-26
Ramucirumab plus Irinotecan / Leucovorin / 5-FU versus Ramucirumab plus Paclitaxel in patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed one prior line of palliative chemotherapy - The Phase II/III RAMIRIS STUDY
Active, not recruitingCTIS2024-512934-14-00
Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbHadvanced or metastatic adenocarcinoma of the stomach or gastroesophageal junctions, who failed prior line of palliative chemotherpay
Start: 2016-11-07Target: 319Updated: 2025-06-23
A Phase 3, Multicenter, Randomized, Open-label Trial of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy With or Without Radiotherapy as Adjuvant Treatment for HER2-Expressing (IHC 3+/2+) Endometrial Cancer (DESTINY-Endometrial02/ GOG-3122/ ENGOT-en30/GINECO)
Not yet recruitingCTIS2024-519444-33-00
Daiichi Sankyo Inc.HER2-expressing endometrial cancer (IHC 3+/2+)
Target: 200Updated: 2026-01-06
A Phase 3 Multicenter, Randomized, Open-label Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab Versus Standard of Care in the First-line Treatment of Patients With Locoregional Recurrence of Squamous Cell Carcinoma of the Head and Neck (HNSCC) With No Distant Metastases
Not yet recruitingCTIS2025-523017-28-00
Rakuten Medical Inc.Locoregional Recurrence of Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Target: 30Updated: 2026-04-03