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Paclitaxel and Cisplatin

DRUG8 trials

Sponsors

Korean Cancer Study Group, Chinese Academy of Medical Sciences, Taizhou Hospital, Peking University, Fudan University

Conditions

Endometrial NeoplasmsEsophageal CancerEsophagus CancerEsophagus SCCNasopharyngeal CarcinomaNeoplasm MetastasisNeoplasm Recurrence, LocalStage III Esophageal Squamous Cell Carcinoma

Phase 1

Safety and Efficacy Study of Icotinib With Intensity-modulated Radiotherapy in Nasopharyngeal Carcinoma
CompletedNCT01534585
Taizhou HospitalNasopharyngeal Carcinoma
Start: 2012-02-29End: 2015-02-28Updated: 2018-04-17

Phase 2

Paclitaxel and Cisplatin for Thymic Neoplasm
TerminatedNCT00818090
Korean Cancer Study GroupThymic Carcinoma, Thymoma
Start: 2008-09-30End: 2011-11-30Updated: 2013-04-12
A Study on Predictive Value of ERCC1 in Esophageal Cancer Patients Treated With Paclitaxel and Cisplatin
NCT01444547
Chinese Academy of Medical SciencesEsophageal Cancer
Start: 2007-01-31End: 2015-12-31Target: 92Updated: 2014-05-06
Combination Treatment of S-1 With Paclitaxel in Advanced Esophageal Cancer
TerminatedNCT01704690
Peking UniversityEsophageal Cancer
Start: 2012-08-31End: 2017-03-31Updated: 2017-04-07
Neoadjuvant Immunotherapy to ESCC
WithdrawnNCT04625543
Qilu Hospital of Shandong UniversityEsophagus SCC
Start: 2020-12-31End: 2023-09-30Updated: 2022-04-26
Combination of Cadonilimab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-006)
Active, not recruitingNCT06143748
Sun Yat-sen UniversityEsophagus Cancer
Start: 2024-03-02End: 2027-12-31Target: 46Updated: 2026-04-23
Cadonilimab With Chemoradiation for Recurrent and Oligometastatic Endometrial Carcinoma
RecruitingNCT06532539
Shandong Cancer Hospital and InstituteEndometrial Neoplasms, Neoplasm Metastasis, Neoplasm Recurrence, Local
Start: 2024-06-13End: 2026-09-01Target: 30Updated: 2026-04-24

Phase 3

A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer
CompletedNCT02459457
Fudan UniversityStage III Esophageal Squamous Cell Carcinoma
Start: 2015-07-01End: 2022-02-28Updated: 2022-02-09

Related Papers

Efficacy and safety of cadonilimab combined with chemotherapy as the first-line treatment for primary advanced or recurrent endometrial cancer: a prospective single-arm open-label phase II clinical trial
BMJ Open2025-05-01
Comparison of 3 Paclitaxel-Based Chemoradiotherapy Regimens for Patients With Locally Advanced Esophageal Squamous Cell Cancer
JAMA Network Open2022-02-2168 citations
Preoperative pembrolizumab combined with chemoradiotherapy for esophageal squamous cell carcinoma: Trial design.
2021-11-1023 citations
Final results of a phase III randomized trial of comparison of three paclitaxel-based regimens concurrent with radiotherapy for patients with local advanced esophageal squamous cell carcinoma.
Journal of Clinical Oncology2020-05-202 citations
Safety results of a phase III randomized trial of comparison of three paclitaxel-based regimens concurrent with radiotherapy for patients with local advanced esophageal squamous cell carcinoma (ESO-Shanghai 2).
Journal of Clinical Oncology2019-05-20
Comparison of paclitaxel in combination with cisplatin (TP), carboplatin (TC) or fluorouracil (TF) concurrent with radiotherapy for patients with local advanced oesophageal squamous cell carcinoma: a three-arm phase III randomized trial (ESO-Shanghai 2)
BMJ Open2018-10-017 citations
A phase II trial of concurrent chemoradiotherapy with weekly paclitaxel and carboplatin in advanced oesophageal carcinoma.
2018-02-1212 citations
A phase II study of concurrent chemoradiotherapy combined with a weekly paclitaxel and 5-fluorouracil regimen to treat patients with advanced oesophageal carcinoma
Radiation Oncology2017-03-077 citations