oXiris membrane

DEVICE4 trials

Sponsors

St. Petersburg State Pavlov Medical University, Centre Hospitalier Universitaire Dijon, Seoul National University Hospital, Samsung Medical Center

Conditions

Acute Kidney Injury Due to Circulatory Failure (Disorder)Acute Kidney Injury Due to SepsisCardiogenic Shock

Unknown Phase

The Effects of Oxiris on Systemic Inflammation and Endothelial dysFunction

St. Petersburg State Pavlov Medical UniversityAcute Kidney Injury Due to Circulatory Failure (Disorder)

Start: 2020-08-17End: 2022-06-01Target: 50Updated: 2020-09-02

Evaluation of Oxiris Membrane as a Treatment for Ischemia-reperfusion Syndrome in Cardiogenic Shock Treated With Extracorporeal Life Support (ECMO/ECLS): A Randomized Pilot Study ECMORIX

CompletedNCT04886180

Centre Hospitalier Universitaire DijonCardiogenic Shock

Start: 2021-05-18End: 2023-03-10Updated: 2026-07-16

Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

RecruitingNCT05575024

Seoul National University HospitalAcute Kidney Injury Due to Sepsis

Start: 2024-01-01End: 2026-12-31Target: 98Updated: 2025-05-15

The Effects of oXiris in Cardiogenic Shock Requiring VA-ECMO

CompletedNCT05642273

Samsung Medical CenterCardiogenic Shock

Start: 2022-11-25End: 2024-01-08Updated: 2024-03-29

Related Papers

Endotoxin removal by the OXIRIS filter for cardiogenic shock requiring veno-arterial extra-corporeal life support: the ECMORIX randomized controlled trial.

2025-07-08

The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label, randomized controlled pilot study

Critical Care2025-06-203 citations

The admission level of CRP during cardiogenic shock is a strong independent risk marker of mortality.

2024-07-164 citations

Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Single-Blind, Randomized Controlled Trial

Frontiers in Cardiovascular Medicine2021-10-1111 citations