Oxaliplatin AqVida 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung
Sponsors
Transthera Sciences (Nanjing) Inc., BioNTech SE, Enliven Therapeutics Inc., Daiichi Sankyo Inc., Glaxosmithkline Research & Development Limited
Conditions
26.0)Cholangiocarcinoma (LTTColorectal Cancer and Breast CancerLocally Advanced or Metastatic HER2 positive Gastric or Gastroesophageal Junction CancerMMRp/ MSS colon cancerMetastatic KRAS G12D-Mutated Colorectal AdenocarcinomaResected (R0 or R1) pancreatic ductal adenocarcinomaSolid Tumors
Phase 1
A Phase I/randomized Phase II, open-label multicenter trial to evaluate the safety, tolerability, and efficacy of mFOLFIRINOX with or without BNT321 as adjuvant therapy following curative resection in patients with pancreatic adenocarcinoma
WithdrawnCTIS2023-506014-47-00
Target: 117Updated: 2024-02-19
A Phase 1a/1b Study of ELVN-002 Combined with Trastuzumab in Advanced Stage HER2+ Solid tumors, and ELVN-002 Combined with Trastuzumab and Chemotherapy in Advanced Stage HER2+ Colorectal Cancer and Breast Cancer
Active, not recruitingCTIS2023-509716-29-00
Start: 2024-09-23Target: 156Updated: 2025-11-24
Phase 2
A Phase 2, open label, randomized study of neoadjuvant dostarlimab plus CAPEOX versus CAPEOX in participants with previously untreated T4N0 or Stage III MMRp/ MSS colon cancer
RecruitingCTIS2024-513441-36-00
Start: 2024-11-27Target: 170Updated: 2025-12-18
A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, With and Without an Anti-EGFR Antibody, and With an Anti-EGFR Antibody and Chemotherapy, in Patients With Metastatic KRAS G12D-Mutated Colorectal Adenocarcinoma (TARGET-D 203)
Not yet recruitingCTIS2026-526473-42-00
Target: 15Updated: 2026-10-21
Phase 3
A Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib versus Physician’s Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR) altered, Chemotherapy- and FGFR Inhibitor-Refractory/Relapsed Cholangiocarcinoma (FIRST-308)
RecruitingCTIS2023-505660-11-00
Start: 2024-04-24Target: 95Updated: 2026-01-26
A Multicenter, Randomized, Open-Label, Phase 3 Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus Or Minus Pembrolizumab as First-Line Treatment in Participants with Unresectable, Locally Advanced or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (GEJ) Cancer (DESTINY-Gastric05)
RecruitingCTIS2024-513122-27-00
Start: 2025-06-10Target: 214Updated: 2025-11-07