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Oxaliplatin 5mg/ml concentrate for solution for infusion

DRUG7 trials

Sponsors

Leap Therapeutics Inc., Glaxosmithkline Research & Development Limited, Amsterdam UMC, Pfizer Inc., AbbVie Deutschland GmbH & Co. KG

Conditions

Colorectal CancerColorectal cancer (BRAF V600E-mutant mCRC)Gastric AdenocarcinomaGastric cancerGastroEsophageal CancerParticipants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon CancerRectum cancerRelapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Phase 1

Phase 2

Phase 3

A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy versus Standard of Care in Participants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Active, not recruitingCTIS2023-503265-27-00
Glaxosmithkline Research & Development LimitedParticipants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Start: 2023-11-23Target: 477Updated: 2025-10-20
C4221015 - AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E MUTANT COLORECTAL CANCER
Active, not recruitingCTIS2023-509405-77-00
Pfizer Inc.Colorectal cancer (BRAF V600E-mutant mCRC)
Start: 2021-02-16Target: 300Updated: 2026-01-26
C4221015 - AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E MUTANT COLORECTAL CANCER
Active, not recruitingCTIS2023-509405-77-00
Pfizer Inc.Colorectal cancer (BRAF V600E-mutant mCRC)
Start: 2021-02-16Target: 300Updated: 2026-01-26
A Phase 3, Multicenter, Randomized, Open-Label Study of Epcoritamab Plus Lenalidomide Compared to Rituximab Plus Gemcitabine and Oxaliplatin in Participants with Relapsed or Refractory Diffuse Large B-Cell Lymphoma
RecruitingCTIS2024-510965-41-00
AbbVie Deutschland GmbH & Co. KGRelapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Start: 2024-09-03Target: 116Updated: 2025-12-15

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