OTL38

DRUG7 trials

Sponsors

On Target Laboratories, LLC, University of Pennsylvania, Chandru Sundaram, Abramson Cancer Center at Penn Medicine

Conditions

Bladder CancerGastric CancerNeoplasmsOvarian CancerPituitary NeoplasmsRenal Cell Carcinoma

Phase 1

Intraoperative Imaging of Pulmonary Nodules by OTL38

CompletedNCT02602119

University of PennsylvaniaNeoplasms

Start: 2015-05-31End: 2022-05-31Updated: 2022-06-28

Intraoperative Imaging of Pituitary Adenomas by OTL

TerminatedNCT02629549

University of PennsylvaniaNeoplasms, Pituitary Neoplasms

Start: 2015-10-31End: 2018-08-03Updated: 2019-08-06

OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer

WithdrawnNCT04941378

Abramson Cancer Center at Penn MedicineOvarian Cancer

Start: 2022-05-28End: 2022-05-28Updated: 2022-06-27

Phase 2

Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer

CompletedNCT02317705

On Target Laboratories, LLCOvarian Cancer

Start: 2014-12-31End: 2015-11-30Updated: 2022-06-21

Phase 3

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

CompletedNCT03180307

On Target Laboratories, LLCOvarian Cancer

Start: 2018-01-26End: 2020-10-16Updated: 2022-02-04

Unknown Phase

Intraoperative Folate Targeted Fluorescence in Renal Cell Carcinoma

CompletedNCT02645409

Chandru SundaramRenal Cell Carcinoma

Start: 2015-12-29End: 2019-04-02Updated: 2020-02-25

Solid Tumor Cancer Surgery With or Without Intraoperative Imaging: A Registry

CompletedNCT02852252

University of PennsylvaniaBladder Cancer, Gastric Cancer

Start: 2016-07-31End: 2020-02-29Updated: 2021-06-18

Related Papers

Phase 3, randomized, single-dose, open-label study to investigate the safety and efficacy of pafolacianine sodium injection (OTL38) for intraoperative imaging of folate receptor positive ovarian cancer.

Journal of Clinical Oncology2021-05-2023 citations

An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas.

2018-02-0529 citations