Oritavancin
Sponsors
Melinta Therapeutics LLC, Targanta Therapeutics Corporation, Melinta Therapeutics, LLC, Melinta Therapeutics, Inc., The Medicines Company
Conditions
AbscessAcute Bacterial Skin and Skin Structure InfectionAcute Bacterial Skin and Skin Structure InfectionsBacteremiaCellulitisGram-Positive Bacterial InfectionsGram-positive Bacterial InfectionsHealthy
Phase 1
Open Label, Dose-finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Participants With Suspected or Confirmed Bacterial Infections
CompletedNCT02134301
Start: 2014-05-31End: 2025-11-04Updated: 2025-12-12
Oritavancin on the Results of Multiple Coagulation Tests in Healthy Volunteers
CompletedNCT02357524
Start: 2015-01-31End: 2015-03-31Updated: 2023-12-19
Multiple Oritavancin Doses on Safety, Tolerability, and Pharmacokinetics in Healthy Subjects
CompletedNCT02470702
Start: 2015-06-30End: 2015-10-31Updated: 2023-12-19
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a New Formulation of Oritavancin in Healthy Volunteers
CompletedNCT02471690
Start: 2015-07-31End: 2016-04-30Updated: 2023-12-19
Phase 2
A Study for Patients With Complicated Skin and Skin Structure Infections
CompletedNCT00514527
Start: 2007-08-31End: 2008-05-31Target: 294Updated: 2008-08-14
A MULTICENTER, OPEN-LABEL, EVALUATOR-BLINDED, RANDOMIZED STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF SINGLE-DOSE INTRAVENOUS ORITAVANCIN FOR THE TREATMENT OF PEDIATRIC SUBJECTS WITH ACUTE BACTERIAL SKIN AND SKIN STRUCTURE INFECTIONS
CompletedCTIS2024-516385-10-00
Start: 2023-05-02End: 2025-11-07Target: 292Updated: 2025-11-25
Phase 4
A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
CompletedNCT02452918
Start: 2015-09-29End: 2016-07-05Updated: 2023-12-20
Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and Skin Structure Infection
CompletedNCT02925416
Start: 2017-01-24End: 2017-06-20Updated: 2024-02-01
Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use
TerminatedNCT05521880
Start: 2024-07-15End: 2025-05-23Updated: 2025-05-29