Organoid Drug Sensitivity Testing-Guided Therapy

DRUG4 trials

Sponsors

Peking Union Medical College Hospital, Eastern Hepatobiliary Surgery Hospital

Conditions

Advanced Biliary Tract Cancer(BTC)Extensive-stage Small Cell Lung Cancer (ES-SCLC)Extensive-stage Small Cell Lung Cancer (SCLC)Hepatocellular Carcinoma ResectableSmall Cell Lung Cancer ( SCLC )Unresectable Hepatocellular Carcinoma

Phase 2

Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung Cancer

Not yet recruitingNCT07106528

Peking Union Medical College HospitalExtensive-stage Small Cell Lung Cancer (ES-SCLC), Extensive-stage Small Cell Lung Cancer (SCLC), Small Cell Lung Cancer ( SCLC )

Start: 2025-08-31End: 2028-12-31Target: 128Updated: 2025-08-06

A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma

Not yet recruitingNCT07351513

Eastern Hepatobiliary Surgery HospitalUnresectable Hepatocellular Carcinoma

Start: 2026-01-30End: 2028-12-31Target: 94Updated: 2026-01-20

A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Biliary Tract Cancers

Not yet recruitingNCT07351591

Eastern Hepatobiliary Surgery HospitalAdvanced Biliary Tract Cancer(BTC)

Start: 2026-01-30End: 2027-12-31Target: 88Updated: 2026-01-20

Drug Sensitivity Testing-Based Tumor Organoids to Guide Adjuvant Therapy After Hepatectomy for Primary Liver Cancer

Not yet recruitingNCT07363356

Eastern Hepatobiliary Surgery HospitalHepatocellular Carcinoma Resectable

Start: 2026-01-30End: 2028-11-30Target: 56Updated: 2026-01-23