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oral vinorelbine

DRUG7 trials

Sponsors

National Cancer Centre, Singapore, Centre Oscar Lambret, IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy, Chinese Academy of Medical Sciences, SOLTI Breast Cancer Research Group

Conditions

Advanced Stage IIIBBreast CancerCarcinoma, Non-Small-Cell LungHigh Thymidylate Synthase ExpressionLow-Grade GliomaNon Small Cell Lung CancerNon-Small Cell Lung CancerSecondary

Early Phase 1

Phase 0 Study of Metronomic Oral Vinorelbine and Letrozole in HR+/HER2-negative Early Breast Cancer Patients (VENTANA)
CompletedNCT02802748
SOLTI Breast Cancer Research GroupBreast Cancer
Start: 2016-07-31End: 2018-01-31Updated: 2018-09-20

Phase 1

Study of Combination of Metronomic Oral Vinorelbine and Sorafenib in Patients With Advanced Non-small Cell Lung Cancer
CompletedNCT00870532
National Cancer Centre, SingaporeNon-Small Cell Lung Cancer
Start: 2008-06-30End: 2013-09-30Updated: 2013-11-04

Phase 2

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma
CompletedNCT02197637
Centre Oscar LambretLow-Grade Glioma
Start: 2014-05-31End: 2020-10-31Updated: 2020-11-18
GEfitinib Plus viNOrelbine in Advanced EGFR Mutated NSCLC. GENOA Trial
NCT02319577
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, ItalyNon Small Cell Lung Cancer
Start: 2012-03-31End: 2015-12-31Target: 80Updated: 2014-12-18
Study of Apatinib Combined With Oral Vinorelbine in Metastatic HER2 Negative Breast Cancer
NCT02768415
Chinese Academy of Medical SciencesBreast Cancer
Start: 2016-06-30Updated: 2019-06-19
Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression
TerminatedNCT02919462
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSAdvanced Stage IIIB, Carcinoma, Non-Small-Cell Lung, High Thymidylate Synthase Expression +1
Start: 2016-03-31End: 2017-05-31Updated: 2018-01-16
Study of Oral Vinorelbine Plus Capecitabine Versus Taxane-gemcitabine Combinations as 1st Line Chemotherapy in Metastatic Breast Cancer
CompletedNCT03887130
Pierre Fabre MedicamentBreast Cancer
Start: 2007-03-27End: 2013-04-18Updated: 2024-04-30

Related Papers

Abstract P2-05-18: Molecular effects of short pre-operative endocrine therapy in hormone receptor-positive and HER2-negative early breast cancer
Clinical Cancer Research2025-06-13
Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial.
2019-09-1825 citations
Anti-proliferative effect of oral metronomic vinorelbine in PAM50 Luminal/HER2-negative early breast cancer (SOLTI-1501 VENTANA): An open-label, randomized, three-arm, multicenter, window-of-opportunity study
Annals of Oncology2018-10-01
Apatinib plus vinorelbine: A novel combination of all-oral regimen in heavily pretreated patients with metastatic HER2-negative breast cancer.
Journal of Clinical Oncology2018-05-20
Phase II study of apatinib plus vinorelbine, a novel combination of all-oral regimen in heavily pretreated patients with metastatic HER2-negative breast cancer.
Journal of Clinical Oncology2017-05-20