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DRUG5 trials

Sponsors

Leiden University Medical Center, Amsterdam UMC, Syddansk Universitet (University of Southern Denmark), Universitair Medisch Centrum Groningen

Conditions

MigraineTransgender women using long-term gender-affirming hormone therapyprosthetic joint infectionrelapsed / refractory multiple myelomarelapsed/refractory multiple myeloma

Phase 1

The headache-inducing effects of cilostazol in men and women with migraine without aura
RecruitingCTIS2025-521520-29-00
Syddansk Universitet (University of Southern Denmark)Migraine
Start: 2025-11-21Target: 29Updated: 2025-06-20

Phase 2

ICON study: A phase 2 study of CC220 (iberdomide) combined with low-dose cyclophosphamide and dexamethasone in relapsed/refractory multiple myeloma (IberCd)
Not yet recruitingCTIS2023-508902-66-00
Amsterdam UMCrelapsed / refractory multiple myeloma
Target: 60Updated: 2026-01-09

Phase 3

HO183 CAR T: A phase III randomized trial comparing academically produced BCMA-directed CAR T-cells (ARI0002h) with standard of care regimen in patients with relapsed/refractory multiple myeloma
Not yet recruitingCTIS2025-524876-43-00
Universitair Medisch Centrum Groningenrelapsed/refractory multiple myeloma
Target: 126Updated: 2026-04-29

Phase 4

Rifampicin Combination Therapy versus Targeted Antimicrobial Monotherapy in the Oral Antimicrobial Treatment Phase of Staphylococcal Prosthetic Joint Infection
RecruitingCTIS2022-501620-26-00
Leiden University Medical Centerprosthetic joint infection
Start: 2023-05-15Target: 316Updated: 2025-07-07
Short-term changes in cardiovascular risk determinants after temporarily stopping gender-affirming hormone therapy in older transgender women - a pilot study
CompletedCTIS2023-505143-39-00
Amsterdam UMCTransgender women using long-term gender-affirming hormone therapy
Start: 2024-02-23End: 2025-09-29Target: 30Updated: 2023-09-15

Related Papers

RIFAMPICIN COMBINATION THERAPY VERSUS TARGETED ANTIMICROBIAL MONOTHERAPY IN THE ORAL ANTIMICROBIAL TREATMENT PHASE OF STAPHYLOCOCCAL PROSTHETIC JOINT INFECTION (RICOTTA-TRIAL): PROTOCOL FOR A RANDOMIZED, CONTROLLED, OPEN-LABEL, NON-INFERIORITY TRIAL
Orthopaedic Proceedings2024-11-221 citations