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DRUG4 trials

Sponsors

Leiden University Medical Center, Amsterdam UMC, Syddansk Universitet (University of Southern Denmark)

Conditions

MigraineTransgender women using long-term gender-affirming hormone therapyprosthetic joint infectionrelapsed / refractory multiple myeloma

Phase 1

The headache-inducing effects of cilostazol in men and women with migraine without aura

RecruitingCTIS2025-521520-29-00

Syddansk Universitet (University of Southern Denmark)Migraine

Start: 2025-11-21Target: 29Updated: 2025-06-20

Phase 2

ICON study: A phase 2 study of CC220 (iberdomide) combined with low-dose cyclophosphamide and dexamethasone in relapsed/refractory multiple myeloma (IberCd)

Not yet recruitingCTIS2023-508902-66-00

Amsterdam UMCrelapsed / refractory multiple myeloma

Target: 60Updated: 2026-01-09

Phase 4

Rifampicin Combination Therapy versus Targeted Antimicrobial Monotherapy in the Oral Antimicrobial Treatment Phase of Staphylococcal Prosthetic Joint Infection

RecruitingCTIS2022-501620-26-00

Leiden University Medical Centerprosthetic joint infection

Start: 2023-05-15Target: 316Updated: 2025-07-07

Short-term changes in cardiovascular risk determinants after temporarily stopping gender-affirming hormone therapy in older transgender women - a pilot study

CompletedCTIS2023-505143-39-00

Amsterdam UMCTransgender women using long-term gender-affirming hormone therapy

Start: 2024-02-23End: 2025-09-29Target: 30Updated: 2023-09-15

Related Papers

RIFAMPICIN COMBINATION THERAPY VERSUS TARGETED ANTIMICROBIAL MONOTHERAPY IN THE ORAL ANTIMICROBIAL TREATMENT PHASE OF STAPHYLOCOCCAL PROSTHETIC JOINT INFECTION (RICOTTA-TRIAL): PROTOCOL FOR A RANDOMIZED, CONTROLLED, OPEN-LABEL, NON-INFERIORITY TRIAL

Orthopaedic Proceedings2024-11-221 citations