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Omaveloxolone

DRUG14 trials

Sponsors

Biogen

Conditions

Friedreich AtaxiaHealth Adult SubjectsHealthyHealthy Adult SubjectsHealthy VolunteerMelanomaMetastatic or Incurable Non-small Cell Lung CancerRelapsed, Refractory Melanoma

Phase 1

RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER
CompletedNCT02029729
BiogenMetastatic or Incurable Non-small Cell Lung Cancer, Relapsed, Refractory Melanoma
Start: 2013-12-31End: 2015-10-01Updated: 2025-05-29
A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers
CompletedNCT03664453
BiogenHealthy
Start: 2018-10-29End: 2018-11-20Updated: 2025-05-30
A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone
CompletedNCT04008186
BiogenHealthy Adult Subjects
Start: 2019-06-14End: 2019-08-28Updated: 2025-05-30
An Open-label DDI Study of Omaveloxolone in Healthy Subjects
CompletedNCT05909644
BiogenHealthy Adult Subjects
Start: 2023-07-05End: 2023-08-30Updated: 2025-05-30
A TQTc Study for Omaveloxolone
CompletedNCT05927649
BiogenHealth Adult Subjects
Start: 2023-07-11End: 2023-09-01Updated: 2025-05-30
A Study to Find Out How BIIB141 (Omaveloxolone) is Processed in the Body and to Learn More About Its Safety in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old
RecruitingNCT06054893
BiogenFriedreich Ataxia
Start: 2024-07-01End: 2030-11-22Target: 35Updated: 2026-01-07
A Study to Find Out How BIIB141 (Omaveloxolone) Moves From the Blood Into the Breastmilk of Healthy Women Who Are Breastfeeding or Pumping Milk
CompletedNCT06612879
BiogenHealthy Volunteer
Start: 2024-10-18End: 2025-04-08Updated: 2025-04-22
A Study to Learn How BIIB141 (Omaveloxolone) is Processed in the Body When Taken as Capsules Compared to Sprinkled on Yogurt in Healthy Adults Aged 18 to 55
CompletedNCT07019064
BiogenHealthy Volunteer
Start: 2025-06-11End: 2025-08-19Updated: 2025-09-22
A Study to Learn if Taking BIIB141 (Omaveloxolone) Affects How Omeprazole is Processed in the Body and About BIIB141's Safety in Healthy Adults Aged 18 to 55
CompletedNCT07149415
BiogenHealthy Volunteer
Start: 2025-09-02End: 2025-10-16Updated: 2025-10-23
A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55
RecruitingNCT07297199
BiogenHealthy Volunteer
Start: 2025-12-12End: 2026-04-17Target: 70Updated: 2026-02-12

Phase 3

Unknown Phase

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